Decoding the role of miRNAs in oral cancer pathogenesis: A focus on signaling pathways

AS Doghish, AA El-Husseiny, EG Khidr… - … -Research and Practice, 2023 - Elsevier
Oral cancer (OC) is the predominant type originating in the head and neck region. The
incidence of OC is mostly associated with behavioral risk factors, including tobacco smoking …

The effects of statins on dental and oral health: a review of preclinical and clinical studies

S Tahamtan, F Shirban, M Bagherniya… - Journal of translational …, 2020 - Springer
The statin family of drugs are safe and effective therapeutic agents for the treatment of
arteriosclerotic cardiovascular disease (CVD). Due to a wide range of health benefits in …

Trends in treatment, incidence and survival of hypopharynx cancer: a 20-year population-based study in the Netherlands

JF Petersen, AJ Timmermans, BAC van Dijk… - European Archives of …, 2018 - Springer
Hypopharynx cancer has the worst prognosis of all head and neck squamous cell cancers.
Since the 1990s, a treatment shift has appeared from a total laryngectomy towards organ …

Role played by paraoxonase-2 enzyme in cell viability, proliferation and sensitivity to chemotherapy of oral squamous cell carcinoma cell lines

R Campagna, A Belloni, V Pozzi, A Salvucci… - International Journal of …, 2022 - mdpi.com
Oral squamous cell carcinoma represents the most aggressive and frequent form of head
and neck cancer. Due to drug resistance, the 5-year survival rate of patients with advanced …

Epidemiology of squamous cell carcinoma of the lip in the United States: a population-based cohort analysis

AY Han, EC Kuan, J Mallen-St Clair… - … –Head & Neck …, 2016 - jamanetwork.com
Importance Squamous cell carcinoma of the lip (lip SCC) composes more than 25% of all
oral cancers. Most of the demographic and prognostic indicators for lip SCC are only …

Development and validation of radiomic signatures of head and neck squamous cell carcinoma molecular features and subtypes

C Huang, M Cintra, K Brennan, M Zhou, AD Colevas… - …, 2019 - thelancet.com
Background Radiomics-based non-invasive biomarkers are promising to facilitate the
translation of therapeutically related molecular subtypes for treatment allocation of patients …

Long non-coding RNAs as important biomarkers in laryngeal cancer and other head and neck tumours

AM Cossu, L Mosca, S Zappavigna, G Misso… - International Journal of …, 2019 - mdpi.com
Head and neck carcinoma (HNC) is a heterogeneous disease encompassing a variety of
tumors according to the origin. Laryngeal cancer (LC) represents one of the most frequent …

Free-circulating methylated DNA in blood for diagnosis, staging, prognosis, and monitoring of head and neck squamous cell carcinoma patients: an observational …

A Schröck, A Leisse, L de Vos, H Gevensleben… - Clinical …, 2017 - academic.oup.com
BACKGROUND Circulating cell-free DNA methylation testing in blood has recently received
regulatory approval for screening of colorectal cancer. Its application in other clinical …

Composition and clinical impact of the immunologic tumor microenvironment in oral squamous cell carcinoma

M Boxberg, L Leising, K Steiger… - The Journal of …, 2019 - journals.aai.org
Immunotherapy shows promising results and revolutionizes treatment of oral squamous cell
carcinoma (OSCC). The immunologic microenvironment might have prognostic/predictive …

MicroRNAs in oral cancer: Biomarkers with clinical potential

S Yete, D Saranath - Oral Oncology, 2020 - Elsevier
Oral cancer is the sixteenth most common cancer globally, with a relatively poor five-year
survival rate of 50%. Thus it is imperative to understand the biology of oral cancer and …