Brain aging mechanisms with mechanical manifestations

Y Blinkouskaya, A Caçoilo, T Gollamudi… - Mechanisms of ageing …, 2021 - Elsevier
Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …

Plasma biomarkers for mild cognitive impairment and Alzheimer's disease

F Song, A Poljak, GA Smythe, P Sachdev - Brain research reviews, 2009 - Elsevier
Purpose of review: With the move toward development of disease modifying treatments,
there is a need for more specific diagnosis of early Alzheimer's disease (AD) and mild …

Anatomically interpretable deep learning of brain age captures domain-specific cognitive impairment

C Yin, P Imms, M Cheng, A Amgalan… - Proceedings of the …, 2023 - National Acad Sciences
The gap between chronological age (CA) and biological brain age, as estimated from
magnetic resonance images (MRIs), reflects how individual patterns of neuroanatomic aging …

The Sydney Memory and Ageing Study (MAS): methodology and baseline medical and neuropsychiatric characteristics of an elderly epidemiological non-demented …

PS Sachdev, H Brodaty, S Reppermund… - International …, 2010 - cambridge.org
Background: The Sydney Memory and Ageing Study (Sydney MAS) was initiated in 2005 to
examine the clinical characteristics and prevalence of mild cognitive impairment (MCI) and …

Assessment of cortical degeneration in patients with Parkinson's disease by voxel‐based morphometry, cortical folding, and cortical thickness

JB Pereira, N Ibarretxe‐Bilbao, MJ Marti… - Human brain …, 2012 - Wiley Online Library
Noninvasive brain imaging methods provide useful information on cerebral involution and
degenerative processes. Here we assessed cortical degeneration in 20 nondemented …

[HTML][HTML] Effects of age and sex on subcortical volumes

Y Wang, Q Xu, J Luo, M Hu, C Zuo - Frontiers in aging neuroscience, 2019 - frontiersin.org
Purpose In an increasingly aging society, it is of great importance to consider trajectories of
subcortical volumes at different ages for understanding biological markers of aging. Thus …

In-vivo measurement of cortical morphology: means and meanings

JF Mangin, E Jouvent, A Cachia - Current opinion in neurology, 2010 - journals.lww.com
In-vivo measurement of cortical morphology: means and meanin... : Current Opinion in
Neurology In-vivo measurement of cortical morphology: means and meanings : Current Opinion …

Genetic map of regional sulcal morphology in the human brain from UK biobank data

BB Sun, SJ Loomis, F Pizzagalli, N Shatokhina… - Nature …, 2022 - nature.com
Genetic associations with macroscopic brain structure can provide insights into brain
function and disease. However, specific associations with measures of local brain folding …

Herbal/natural compounds resist hallmarks of brain aging: From molecular mechanisms to therapeutic strategies

J Qiao, C Wang, Y Chen, S Yu, Y Liu, S Yu, L Jiang… - Antioxidants, 2023 - mdpi.com
Aging is a complex process of impaired physiological integrity and function, and is
associated with increased risk of cardiovascular disease, diabetes, neurodegeneration, and …

[HTML][HTML] Relationship between sulcal characteristics and brain aging

K Jin, T Zhang, M Shaw, P Sachdev… - Frontiers in aging …, 2018 - frontiersin.org
This study aimed to determine whether sulcal morphology differs between middle age (MA)
and older healthy individuals. Furthermore, we sought to determine whether age-related …