Gram-negative bacteria characteristically are surrounded by an additional membrane layer,
the outer membrane. Although outer membrane components often play important roles in …

Lipopolysaccharides are critical components of bacterial outer membranes. The more
conserved lipid A part of the lipopolysaccharide molecule is a major element in the …

Bacterial polysaccharides are usually associated with the outer surface of the bacterium.
They can form an amorphous layer of extracellular polysaccharide (EPS) surrounding the …

The O-antigen is an important component of the outer membrane of Gram-negative bacteria.
It is a repeat unit polysaccharide and consists of a number of repeats of an oligosaccharide …

From a historical perspective, the study of both the biochemistry and the genetics of
lipopolysaccharide (LPS) synthesis began with the enteric bacteria. These organisms have …

We report the identification and characterization of the eps gene cluster of Streptococcus
thermophilus Sfi6 required for exopolysaccharide (EPS) synthesis. This report is the first …

The PhoP-PhoQ two-component system is essential for virulence in Salmonella
typhimurium. This system controls expression of some 40 different proteins, yet most PhoP …

Publisher Summary This chapter provides an overview of the molecular mechanisms
involved in synthesis and expression of cell-surface polysaccharides in Gram-negative …

Wzz proteins regulate the degree of polymerization of the O antigen (Oag) subunits in
lipopolysaccharide (LPS) biosynthesis. Although the pathogenic relevance of Oag is well …

Only Vibrio cholerae strains of serotype O1 are known to cause epidemics, while non‐O1
strains are associated with sporadic cases of cholera. It was therefore unexpected that the …