Interactions between purkinje cells and granule cells coordinate the development of functional cerebellar circuits

ME van der Heijden, RV Sillitoe - Neuroscience, 2021 - Elsevier
Cerebellar development has a remarkably protracted morphogenetic timeline that is
coordinated by multiple cell types. Here, we discuss the intriguing cellular consequences of …

Functional outcomes of cerebellar malformations

JS Gill, RV Sillitoe - Frontiers in cellular neuroscience, 2019 - frontiersin.org
The cerebellum is well-established as a primary center for controlling sensorimotor
functions. However, recent experiments have demonstrated additional roles for the …

[HTML][HTML] Shark and ray genomics for disentangling their morphological diversity and vertebrate evolution

S Kuraku - Developmental Biology, 2021 - Elsevier
Developmental studies of sharks and rays (elasmobranchs) have provided much insight into
the process of morphological evolution of vertebrates. Although those studies are …

Meis1 coordinates cerebellar granule cell development by regulating Pax6 transcription, BMP signaling and Atoh1 degradation

T Owa, S Taya, S Miyashita, M Yamashita… - Journal of …, 2018 - Soc Neuroscience
Cerebellar granule cell precursors (GCPs) and granule cells (GCs) represent good models
to study neuronal development. Here, we report that the transcription factor myeloid ectopic …

Time in neurogenesis: conservation of the developmental formation of the cerebellar circuitry

E Rueda-Alaña, F García-Moreno - Brain Behavior and Evolution, 2022 - karger.com
The cerebellum is a conserved structure of vertebrate brains that develops at the most
anterior region of the alar rhombencephalon. All vertebrates display a cerebellum, making it …

The compartmental restriction of cerebellar interneurons

GG Consalez, R Hawkes - Frontiers in neural circuits, 2013 - frontiersin.org
The Purkinje cells (PC's) of the cerebellar cortex are subdivided into multiple different
molecular phenotypes that form an elaborate array of parasagittal stripes. This array serves …

Neonatal hyperoxia perturbs neuronal development in the cerebellum

T Scheuer, Y Sharkovska, V Tarabykin… - Molecular …, 2018 - Springer
Impaired postnatal brain development of preterm infants often results in neurological deficits.
Besides pathologies of the forebrain, maldeveolopment of the cerebellum is increasingly …

The evolution of the vertebrate cerebellum: absence of a proliferative external granule layer in a non‐teleost ray‐finned fish

T Butts, MS Modrell, CVH Baker… - Evolution & …, 2014 - Wiley Online Library
The cerebellum represents one of the most morphologically variable structures in the
vertebrate brain. To shed light on its evolutionary history, we have examined the molecular …

Cerebellar lesions are associated with TSC2 mutations in tuberous sclerosis complex: a retrospective record review study

S Boronat, EA Thiele, P Caruso - Developmental Medicine & …, 2017 - Wiley Online Library
Aim Cerebellar lesions are present in approximately 30% of patients with tuberous sclerosis
complex. Although several prior studies have characterized these lesions, our study …

Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development

V Baubet, C Xiang, A Molczan, L Roccograndi… - …, 2012 - journals.biologists.com
Cerebellum development depends on the correct differentiation of progenitors into neurons,
a process controlled by a transcriptional program that remains poorly understood. Here we …