Multienzyme‐like nanozymes: regulation, rational design, and application

J Sheng, Y Wu, H Ding, K Feng, Y Shen… - Advanced …, 2024 - Wiley Online Library
Nanomaterials with more than one enzyme‐like activity are termed multienzymic
nanozymes, and they have received increasing attention in recent years and hold huge …

Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

H Tian, T Zhang, S Qin, Z Huang, L Zhou, J Shi… - Journal of hematology & …, 2022 - Springer
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Near-infrared phosphorescent carbon dots for sonodynamic precision tumor therapy

B Geng, J Hu, Y Li, S Feng, D Pan, L Feng… - Nature …, 2022 - nature.com
Theranostic sonosensitizers with combined sonodynamic and near infrared (NIR) imaging
modes are required for imaging guided sonodynamic therapy (SDT). It is challenging …

Harnessing nanomaterials for cancer sonodynamic immunotherapy

S Liang, J Yao, D Liu, L Rao, X Chen… - Advanced …, 2023 - Wiley Online Library
Immunotherapy has made remarkable strides in cancer therapy over the past decade.
However, such emerging therapy still suffers from the low response rates and immune …

Chemodynamic therapy via fenton and fenton‐like nanomaterials: strategies and recent advances

C Jia, Y Guo, FG Wu - Small, 2022 - Wiley Online Library
Chemodynamic therapy (CDT), a novel cancer therapeutic strategy defined as the treatment
using Fenton or Fenton‐like reaction to produce• OH in the tumor region, was first proposed …

Doping engineering to modulate lattice and electronic structure for enhanced piezocatalytic therapy and ferroptosis

B Tian, R Tian, S Liu, Y Wang, S Gai, Y Xie… - Advanced …, 2023 - Wiley Online Library
Piezocatalytic therapy, which generates reactive oxygen species (ROS) under mechanical
force, has garnered extensive attention for its use in cancer therapy owing to its deep tissue …

Dual nanozyme-driven PtSn bimetallic nanoclusters for metal-enhanced tumor photothermal and catalytic therapy

Y Zhu, R Zhao, L Feng, C Wang, S Dong, MV Zyuzin… - ACS …, 2023 - ACS Publications
Specific generation of reactive oxygen species (ROS) within tumors in situ catalyzed by
nanozymes is a promising strategy for cancer therapeutics. However, it remains a significant …

Engineering macrophage exosome disguised biodegradable nanoplatform for enhanced sonodynamic therapy of glioblastoma

T Wu, Y Liu, Y Cao, Z Liu - Advanced Materials, 2022 - Wiley Online Library
Sonodynamic therapy (SDT) exhibits high tissue penetration and negligible radiation
damage to normal tissues, and thus emerges as a promising cancer therapeutic modality for …

Manipulating intratumoral fenton chemistry for enhanced chemodynamic and chemodynamic‐synergized multimodal therapy

Y Zhou, S Fan, L Feng, X Huang, X Chen - Advanced Materials, 2021 - Wiley Online Library
Chemodynamic therapy (CDT) uses the tumor microenvironment‐assisted intratumoral
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …

Advanced biotechnology-assisted precise sonodynamic therapy

Y Zhang, X Zhang, H Yang, L Yu, Y Xu… - Chemical Society …, 2021 - pubs.rsc.org
Despite significant advances, the therapeutic impact of photodynamic therapy is still
substantially hampered by the restricted penetration depth of light and the reactive oxygen …