Background: Diffuse axonal injury (DAI) is one of the most common and important pathologic
features of traumatic brain injury (TBI). The susceptibility of axons to mechanical injury …

This article comprehensively reviews the lateral fluid percussion (LFP) model of traumatic
brain injury (TBI) in small animal species with particular emphasis on its validity, clinical …

Every year, an estimated 1.7 million Americans sustain brain injury. Long-term disabilities
impact nearly half of moderate brain injury survivors and nearly 50,000 of these cases result …

Axonal damage is one of the most common and important pathologic features of traumatic
brain injury. Severe diffuse axonal injury, resulting from inertial forces applied to the head, is …

The temporal pattern of apoptosis in the adult rat brain after lateral fluid-percussion (FP)
brain injury was characterized using terminal deoxynucleotidyl-transferase-mediated biotin …

The pathophysiology of brain and spinal cord injury (SCI) is complex and involves multiple
injury mechanisms that are spatially and temporally specific. It is now appreciated that many …

The regulation of brain temperature is largely dependent on the metabolic activity of brain
tissue and remains complex. In intensive care clinical practice, the continuous monitoring of …

Traumatic brain injury (TBI) in humans may cause extensive sensorimotor and cognitive
dysfunction. As a result, many TBI researchers are beginning to assess behavioral …

The mechanisms underlying secondary or delayed cell death following traumatic brain injury
are poorly understood. Recent evidence from experimental models suggests that …

This review is a critical appraisal of the widespread assumption that high extracellular
glutamate, resulting from enhanced pre-synaptic release superimposed on deficient uptake …