Research on astronaut health and model organisms have revealed six features of
spaceflight biology that guide our current understanding of fundamental molecular changes …

Remarkable progress has been made in the development of new therapies for cancer,
dramatically changing the landscape of treatment approaches for several malignancies and …

NASA's plans for space exploration include a return to the Moon to stay—boots back on the
lunar surface with an orbital outpost. This station will be a launch point for voyages to …

Spaceflight is known to impose changes on human physiology with unknown molecular
etiologies. To reveal these causes, we used a multi-omics, systems biology analytical …

Human exploration of the Moon is associated with substantial risks to astronauts from space
radiation. On the surface of the Moon, this consists of the chronic exposure to galactic …

Risks to health are the prime consideration in all human situations of ionizing radiation
exposure and therefore of relevance to radiation protection in all occupational, medical, and …

On Earth, humans are subjected to a gravitational force that has been an important
determinant in human evolution and function. During spaceflight, astronauts are subjected to …

With current plans for manned missions to Mars and beyond, the need to better understand,
prevent, and counteract the harmful effects of long-duration spaceflight on the body is …

Cardiac ageing manifests as a decline in function leading to heart failure. At the cellular
level, ageing entails decreased replicative capacity and dysregulation of cellular processes …

With the construction of the International Space Station, humans have been continuously
living and working in space for 22 years. Microbial studies in space and other extreme …