Dry Eye Disease in the Middle East and Northern Africa: a position paper on the current state and unmet needs

S Lazreg, M Hosny, MA Ahad, MM Sinjab… - Clinical …, 2024 - Taylor & Francis
Abstract In the Middle East and Northern Africa (MENA), dry eye disease (DED) is often
misdiagnosed or overlooked. This review summarizes a series of conversations with …

BCLA CLEAR-Effect of contact lens materials and designs on the anatomy and physiology of the eye

PB Morgan, PJ Murphy, KL Gifford, P Gifford… - Contact Lens and …, 2021 - Elsevier
This paper outlines changes to the ocular surface caused by contact lenses and their degree
of clinical significance. Substantial research and development to improve oxygen …

Exploring Signs and Symptoms Associated with Meibomian Gland Dysfunction for Use as Clinical Trial Endpoints

L Ajouz, A Nguyen, C Zhao, MR Robinson… - Journal of Ocular …, 2023 - liebertpub.com
Purpose: Dry eye disease is attributed to impaired tear production and/or evaporative dry
eye. Evaporative dry eye is frequently associated with meibomian gland dysfunction (MGD) …

Association of tear matrix metalloproteinase 9 immunoassay with signs and symptoms of dry eye disease: A cross-sectional study using qualitative, semiquantitative …

YH Lee, SP Bang, KY Shim, MJ Son, H Kim, JH Jun - PLoS One, 2021 - journals.plos.org
Purpose This study aimed to analyze the association of tear matrix metalloproteinase 9
(MMP-9) immunoassay with the severity of dry eye (DE) signs and symptoms through …

Perfluorohexyloctane ophthalmic solution: a review of a prescription treatment for dry eye disease that directly targets tear evaporation

PM Karpecki, JD Sheppard - Expert Review of Ophthalmology, 2023 - Taylor & Francis
Introduction Perfluorohexyloctane (PFHO) ophthalmic solution (brand name, MIEBO) was
recently approved by the United States Food and Drug Administration to treat the signs and …

[PDF][PDF] Evaporation in Dry Eye Disease

OD Paul Karpecki - alleyesonevaporation.com
CURRENT THINKING ON DED TREATMENT Although excessive evaporation is a central
mechanism in DED, currently available prescription treatments do not target evaporation …