Aflatoxin biosynthesis and genetic regulation: A review

I Caceres, A Al Khoury, R El Khoury, S Lorber… - Toxins, 2020 - mdpi.com
The study of fungal species evolved radically with the development of molecular techniques
and produced new evidence to understand specific fungal mechanisms such as the …

Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and …

JC Frisvad, LLH Møller, TO Larsen, R Kumar… - Applied Microbiology …, 2018 - Springer
This review presents an update on the current knowledge of the secondary metabolite
potential of the major fungal species used in industrial biotechnology, ie, Aspergillus niger …

Regulation of fungal secondary metabolism

AA Brakhage - Nature Reviews Microbiology, 2013 - nature.com
Fungi produce a multitude of low-molecular-mass compounds known as secondary
metabolites, which have roles in a range of cellular processes such as transcription …

Aspergillus flavus

S Amaike, NP Keller - Annual review of phytopathology, 2011 - annualreviews.org
Aspergillus flavus is saprophytic soil fungus that infects and contaminates preharvest and
postharvest seed crops with the carcinogenic secondary metabolite aflatoxin. The fungus is …

Coordination of secondarymetabolism and development in fungi: the velvet familyof regulatory proteins

Ö Bayram, GH Braus - FEMS microbiology reviews, 2012 - academic.oup.com
Filamentous fungi produce a number of small bioactive molecules as part of their secondary
metabolism ranging from benign antibiotics such as penicillin to threatening mycotoxins …

Advanced mycotoxin control and decontamination techniques in view of an increased aflatoxin risk in Europe due to climate change

M Loi, AF Logrieco, T Pusztahelyi, É Leiter… - Frontiers in …, 2023 - frontiersin.org
Aflatoxins are toxic secondary metabolites produced by Aspergillus spp. found in staple food
and feed commodities worldwide. Aflatoxins are carcinogenic, teratogenic, and mutagenic …

Biosynthesis and toxicological effects of patulin

O Puel, P Galtier, IP Oswald - Toxins, 2010 - mdpi.com
Patulin is a toxic chemical contaminant produced by several species of mold, especially
within Aspergillus, Penicillium and Byssochlamys. It is the most common mycotoxin found in …

Current understanding on aflatoxin biosynthesis and future perspective in reducing aflatoxin contamination

J Yu - Toxins, 2012 - mdpi.com
Traditional molecular techniques have been used in research in discovering the genes and
enzymes that are involved in aflatoxin formation and genetic regulation. We cloned most, if …

Secondary metabolism: regulation and role in fungal biology

EM Fox, BJ Howlett - Current opinion in microbiology, 2008 - Elsevier
Filamentous fungi produce a diverse array of secondary metabolites–small molecules that
are not necessary for normal growth or development. Secondary metabolites have a …

From genomics to metabolomics, moving toward an integrated strategy for the discovery of fungal secondary metabolites

T Hautbergue, EL Jamin, L Debrauwer, O Puel… - Natural Product …, 2018 - pubs.rsc.org
Fungal secondary metabolites are defined by bioactive properties that ensure adaptation of
the fungus to its environment. Although some of these natural products are promising …