Immobilization of lipases on hydrophobic supports: immobilization mechanism, advantages, problems, and solutions

RC Rodrigues, JJ Virgen-Ortíz, JCS Dos Santos… - Biotechnology …, 2019 - Elsevier
Lipases are the most widely used enzymes in biocatalysis, and the most utilized method for
enzyme immobilization is using hydrophobic supports at low ionic strength. This method …

Isocyanide-based multi-component reactions for carrier-free and carrier-bound covalent immobilization of enzymes

M Mohammadi, M Shahedi, F Ahrari, M Mostafavi… - Nature …, 2023 - nature.com
Strategies for the covalent immobilization of enzymes depend on the type of functional group
selected to perform the coupling reaction, and on the relative importance of selectivity …

Process optimization for biodiesel production from waste cooking oil using multi-enzyme systems through response surface methodology

M Babaki, M Yousefi, Z Habibi, M Mohammadi - Renewable Energy, 2017 - Elsevier
Lipase from Rhizomucor miehei (RML) and lipase B from Candida antarctica (CALB) were
covalently immobilized onto epoxy-functionalized silica. In this study, we developed a multi …

Amination of enzymes to improve biocatalyst performance: Coupling genetic modification and physicochemical tools

RC Rodrigues, O Barbosa, C Ortiz… - RSC …, 2014 - pubs.rsc.org
Improvement of the features of an enzyme is in many instances a pre-requisite for the
industrial implementation of these exceedingly interesting biocatalysts. To reach this goal …

Hyperactivation of lipases by immobilization on superhydrophobic graphene quantum dots inorganic hybrid nanoflower

M Mostafavi, MB Poor, Z Habibi, M Mohammadi… - International Journal of …, 2024 - Elsevier
Various nanoflowers are synthesized for enzyme immobilization. In order to increase the
activity of nanoflowers, in this study, 3D flower-like structured organic–inorganic hybrid …

Preparation of highly reusable biocatalysts by immobilization of lipases on epoxy-functionalized silica for production of biodiesel from canola oil

M Babaki, M Yousefi, Z Habibi, J Brask… - Biochemical …, 2015 - Elsevier
In the present work, lipases from Candida antarctica (CALB), Thermomyces lanuginosus
(TLL) and Rhizomucor miehei (RML) were covalently immobilized on epoxy-functionalized …

Polyethyleneimine-modified superparamagnetic Fe3O4 nanoparticles for lipase immobilization: Characterization and application

M Khoobi, SF Motevalizadeh, Z Asadgol… - Materials Chemistry and …, 2015 - Elsevier
Magnetically separable nanospheres consisting of polyethyleneimine (PEI) and succinated
PEI grafted on silica coated magnetite (Fe 3 O 4) were prepared and characterized using …

Application of multi-component reaction for covalent immobilization of two lipases on aldehyde-functionalized magnetic nanoparticles; production of biodiesel from …

M Ashjari, M Garmroodi, FA Asl, M Emampour… - Process …, 2020 - Elsevier
Lipase from Rhizomucor miehei (RML) and Thermomyces lanuginosa lipase (TLL) were
immobilized on silica core-shell magnetic nanoparticles (Fe 3 O 4@ SiO 2) produced by …

Lipase immobilization onto polyethylenimine coated magnetic nanoparticles assisted by divalent metal chelated ions

SF Motevalizadeh, M Khoobi, A Sadighi… - Journal of Molecular …, 2015 - Elsevier
In this study, polyethylenimine coated Fe 3 O 4 magnetic nanoparticles (Fe@ PEI) were
prepared and used for three metal ions (Co 2+, Cu 2+ and Pd 2+) chelation. The metal …

Covalent binding of hyper-activated Rhizomucor miehei lipase (RML) on hetero-functionalized siliceous supports

M Garmroodi, M Mohammadi, A Ramazani… - International journal of …, 2016 - Elsevier
Physical adsorption onto hydrophobic supports has proven to be an effective way to improve
the activity of lipases. Covalent binding, on the other hand, enhances the active lifetime of …