Neutrophils are abundant in the circulation and are one of the immune system's first lines of
defense against infection. There has been substantial work carried out investigating the role …

Neutrophils are the most abundant leukocytes in human peripheral blood. They form the first
line of defense against invading foreign pathogens and might play a crucial role in malaria …

Acute kidney injury (AKI) is attended by injury-related biomarkers appearing in the urine and
serum, decreased urine output, and impaired glomerular filtration rate. AKI causes increased …

Invasive bacterial disease is well described in immunocompromised hosts, including those
with malaria infection. One bacterial infection frequently observed in children with …

Free heme in plasma acts as a prooxidant; thus, it is bound to hemopexin and eliminated by
the liver. High iron content in the liver can support Plasmodium growth and cause oxidative …

Recent malaria is associated with an increased risk of systemic bacterial infection. The
aetiology of this association is unclear but malaria-related haemolysis may be one …

Abstract Background Subclinical infection with Plasmodium falciparum remains highly
prevalent, yet diagnosing these often low-density infections remains a challenge. Infections …

Neutrophils are the most abundant polymorphonuclear granular leukocytes in human blood
and are an essential part of the innate immune system. Neutrophils are efficient cells that …

Background: Individuals living in malaria-endemic regions develop immunity against severe
malaria, but it is unclear whether immunity against pre-erythrocytic stages that blocks …

One complication of malaria is increased susceptibility to invasive bacterial infections.
Plasmodium infections impair host immunity to non-Typhoid Salmonella (NTS) through …