SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)

AD Proal, MB VanElzakker, S Aleman, K Bach… - Nature …, 2023 - nature.com
Millions of people are suffering from Long COVID or post-acute sequelae of COVID-19
(PASC). Several biological factors have emerged as potential drivers of PASC pathology …

Zika virus infection—after the pandemic

D Musso, AI Ko, D Baud - New England Journal of Medicine, 2019 - Mass Medical Soc
Zika Virus and Its Associated Diseases Zika is a mosquito-borne flavivirus that can cause
congenital defects, including microcephaly. Although most Zika virus infections are …

Field-deployable viral diagnostics using CRISPR-Cas13

C Myhrvold, CA Freije, JS Gootenberg, OO Abudayyeh… - Science, 2018 - science.org
Mitigating global infectious disease requires diagnostic tools that are sensitive, specific, and
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK …

Persistent circulation of soluble and extracellular vesicle‐linked Spike protein in individuals with postacute sequelae of COVID‐19

V Craddock, A Mahajan, L Spikes… - Journal of medical …, 2023 - Wiley Online Library
ABSTRACT SARS‐CoV‐2, the causative agent of COVID‐19 disease, has resulted in the
death of millions worldwide since the beginning of the pandemic in December 2019. While …

Nucleic acid detection with CRISPR-Cas13a/C2c2

JS Gootenberg, OO Abudayyeh, JW Lee… - Science, 2017 - science.org
Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen
detection, genotyping, and disease monitoring. The RNA-guided, RNA-targeting clustered …

[HTML][HTML] Why does viral RNA sometimes persist after recovery from acute infections?

DE Griffin - PLoS biology, 2022 - journals.plos.org
DNA viruses often persist in the body of their host, becoming latent and recurring many
months or years later. By contrast, most RNA viruses cause acute infections that are cleared …

Effects of COVID-19 and mRNA vaccines on human fertility

F Chen, S Zhu, Z Dai, L Hao, C Luan, Q Guo… - Human …, 2022 - academic.oup.com
ABSTRACT The coronavirus disease 2019 (COVID-19), which is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has precipitated a global health crisis of …

An update on Zika virus infection

D Baud, DJ Gubler, B Schaub, MC Lanteri, D Musso - The Lancet, 2017 - thelancet.com
The epidemic history of Zika virus began in 2007, with its emergence in Yap Island in the
western Pacific, followed in 2013–14 by a larger epidemic in French Polynesia, south …

The Zika virus epidemic in Brazil: from discovery to future implications

R Lowe, C Barcellos, P Brasil, OG Cruz… - International journal of …, 2018 - mdpi.com
The first confirmed case of Zika virus infection in the Americas was reported in Northeast
Brazil in May 2015, although phylogenetic studies indicate virus introduction as early as …

SARS-CoV-2 persistence is associated with antigen-specific CD8 T-cell responses

LK Vibholm, SSF Nielsen, MH Pahus, GS Frattari… - …, 2021 - thelancet.com
Abstract Background Upon SARS-CoV-2 infection, most individuals develop neutralizing
antibodies and T-cell immunity. However, some individuals reportedly remain SARS-CoV-2 …