Gut-liver-brain axis is a three-way highway of information interaction system among the
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …

Over the past two decades, whole food supplementation strategies have been leveraged to
target mental health. In addition, there has been increasing attention on the ability of gut …

Objective Obesity and its associated comorbidities represent a global health challenge with
a need for well-tolerated, effective, and mechanistically diverse pharmaceutical …

Background Glucagon-like peptide1 receptor (GLP-1R) agonists have been found to reduce
alcohol drinking in rodents and overweight patients with alcohol use disorder (AUD) …

The brain, particularly the hypothalamus and brainstem, monitors and integrates circulating
metabolic signals, including gut hormones. Gut–brain communication is also mediated by …

Understanding the developmental origins of health and disease is integral to overcome the
global tide of obesity and its metabolic consequences, including atherosclerotic …

Despite the growing popular interest in sleep and diet, many gaps exist in our scientific
understanding of the interaction between circadian rhythms and metabolism. In this Review …

Inappropriate food intake behavior is one of the main drivers for fat mass development
leading to obesity. Importantly the gut microbiota-mediated signals have emerged as key …

The gastrointestinal hormones ghrelin and glucagon-like peptide-1 (GLP-1) have opposite
secretion patterns, as well as opposite effects on metabolism and food intake. Beyond their …

Objective The aim of this study was to compare changes in gastrointestinal hormones and
appetite ratings after a similar weight loss induced by a very low‐energy diet alone or in …