Applications of brain organoids in neurodevelopment and neurological diseases

N Sun, X Meng, Y Liu, D Song, C Jiang… - Journal of Biomedical …, 2021 - Springer
A brain organoid is a self-organizing three-dimensional tissue derived from human
embryonic stem cells or pluripotent stem cells and is able to simulate the architecture and …

[HTML][HTML] Methamphetamine induced neurotoxic diseases, molecular mechanism, and current treatment strategies

P Shrestha, N Katila, S Lee, JH Seo, JH Jeong… - Biomedicine & …, 2022 - Elsevier
Methamphetamine (MA) is a extremely addictive psychostimulant drug with a significant
abuse potential. Long-term MA exposure can induce neurotoxic effects through oxidative …

Increases in methamphetamine use among heroin treatment admissions in the United States, 2008–17

CM Jones, N Underwood, WM Compton - Addiction, 2020 - Wiley Online Library
Abstract Background and Aims Due to their small sample sizes, geographic specificity and
limited examination of socio‐demographic characteristics, recent studies of …

Resurgent methamphetamine use at treatment admission in the United States, 2008–2017

CM Jones, EO Olsen, J O'Donnell… - American Journal of …, 2020 - ajph.aphapublications.org
Objectives. To evaluate trends and correlates of methamphetamine use in the United States.
Methods. Data are from 15 747 334 drug-related treatment admissions among persons aged …

Glial cell diversity and methamphetamine-induced neuroinflammation in human cerebral organoids

J Dang, SK Tiwari, K Agrawal, H Hui, Y Qin… - Molecular …, 2021 - nature.com
Methamphetamine (METH) is a potent stimulant that induces a euphoric state but also
causes cognitive impairment, neurotoxicity and neurodevelopmental deficits. Yet, the …

Methamphetamine use in the United States: epidemiological update and implications for prevention, treatment, and harm reduction

CM Jones, D Houry, B Han, G Baldwin… - Annals of the New …, 2022 - Wiley Online Library
Recent attention has focused on the growing role of psychostimulants, such as
methamphetamine in overdose deaths. Methamphetamine is an addictive and potent …

Methamphetamine induces systemic inflammation and anxiety: the role of the gut–immune–brain axis

M Davidson, M Mayer, A Habib, N Rashidi… - International journal of …, 2022 - mdpi.com
Methamphetamine (METH) is a highly addictive drug abused by millions of users worldwide,
thus becoming a global health concern with limited management options. The inefficiency of …

Neuroimmune mechanisms as novel treatment targets for substance use disorders and associated comorbidities

MD Namba, JM Leyrer-Jackson, EK Nagy… - Frontiers in …, 2021 - frontiersin.org
Recent studies examining the neurobiology of substance abuse have revealed a significant
role of neuroimmune signaling as a mechanism through which drugs of abuse induce …

Methamphetamine (MA) use and MA-induced psychosis are associated with increasing aberrations in the compensatory immunoregulatory system, interleukin-1α …

R Kalayasiri, K Dadwat, S Thika… - Translational …, 2023 - nature.com
There are only a few studies reporting on the immunological profiles of methamphetamine
(MA) use, MA dependency, or MA-induced psychosis (MAP). This study measured M1 …

Drugs and bugs: the gut-brain axis and substance use disorders

S Simpson, R Mclellan, E Wellmeyer, F Matalon… - Journal of Neuroimmune …, 2022 - Springer
Substance use disorders (SUDs) represent a significant public health crisis. Worldwide,
5.4% of the global disease burden is attributed to SUDs and alcohol use, and many more …