Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …

Spray drying is an efficient technology for solid dispersion manufacturing since it allows
extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to …

Application of amorphous solid dispersions (ASDs) is considered one of the most promising
approaches to increase the dissolution rate and extent of bioavailability of poorly water …

The transformation to an amorphous form is one of the most promising approaches to
address the low solubility of drug compounds, the latter being an increasing challenge in the …

The preparation of amorphous solid dispersions (ASDs) is a suitable approach to overcome
solubility-limited absorption of poorly soluble drugs. In particular, pH-dependent soluble …

Objective Interactions between drugs and polymers were utilized to lower the processing
temperature of hot-melt extrusion (HME), and thus minimize the thermal degradation of heat …

Drugs have been classified as fast, moderate, and poor crystallizers based on their inherent
solid-state crystallization tendency. Differential scanning calorimetry-based heat-cool-heat …

Amorphous formulations provide a general approach to improving the solubility and
bioavailability of drugs. Amorphous medicines for global health should resist crystallization …

Inhibiting surface crystallization is an interesting strategy to enhance the physical stability of
amorphous solid dispersions (ASDs), still preserving high drug loads. The aim of this study …

Amorphous solid dispersions (ASD) stand on the forefront of solubilizing formulations for
many poorly soluble drug candidates. It has been widely accepted that the physical stability …