Multimodal interactions of drugs, natural compounds and pollutants with the gut microbiota

AE Lindell, M Zimmermann-Kogadeeva… - Nature Reviews …, 2022 - nature.com
The gut microbiota contributes to diverse aspects of host physiology, ranging from
immunomodulation to drug metabolism. Changes in the gut microbiota composition are …

Use of the concept 'environmentally relevant level'in linking the results of pesticide toxicity studies to public health outcomes

R Mesnage, C Benbrook - All Life, 2023 - Taylor & Francis
Evidence is growing that human exposures to pesticides are contributing in a myriad of
complex ways to chronic disease. Regulatory and public health agencies have struggled for …

[HTML][HTML] Chronic dietary exposure to a glyphosate-based herbicide results in total or partial reversibility of plasma oxidative stress, cecal microbiota abundance and …

M Fréville, A Estienne, C Ramé, G Lefort… - Frontiers in …, 2022 - frontiersin.org
Glyphosate-based herbicides (GBHs) are massively used in agriculture. However, few
studies have investigated the effects of glyphosate-based herbicides on avian species …

Urinary glyphosate and AMPA levels in a cross-sectional study of postmenopausal women: Associations with organic eating behavior and dietary intake

RM Lucia, X Liao, WL Huang, D Forman, A Kim… - International journal of …, 2023 - Elsevier
Animal and epidemiologic studies suggest that there may be adverse health effects from
exposure to glyphosate, the most highly used pesticide in the world, and its metabolite …

[HTML][HTML] Glyphosate and AMPA in human urine of HBM4EU-aligned studies: part B adults

J Buekers, S Remy, J Bessems, E Govarts, L Rambaud… - Toxics, 2022 - mdpi.com
Within HBM4EU, human biomonitoring (HBM) studies measuring glyphosate (Gly) and
aminomethylphosphonic acid (AMPA) in urine samples from the general adult population …

[HTML][HTML] Exposure to Environmental Pesticides and the Risk of Autism Spectrum Disorders: A Population-Based Case-Control Study

P Román, C Ruiz-González, L Rueda-Ruzafa… - Medicina, 2024 - mdpi.com
Background and Objectives: Autism spectrum disorder (ASD) is a neurodevelopmental
condition characterized by challenges in communication, social interactions, and repetitive …

[HTML][HTML] Biological effects of sub-lethal doses of glyphosate and AMPA on cardiac myoblasts

E Arrigo, S Gilardi, L Muratori, S Raimondo… - Frontiers in …, 2023 - frontiersin.org
Introduction: Glyphosate is the active compound of different non-selective herbicides, being
the most used agriculture pesticide worldwide. Glyphosate and AMPA (one of its main …

Molecular dynamics simulation studies on uptake of fipronil sulfone by gut microbiome and its influence on risk for cause of Parkinson's disease

A Bhat, V Chandramohan, S Sabat - Molecular Simulation, 2024 - Taylor & Francis
Biotransformation of Fipronil forms three metabolites: fipronil sulfone, fipronil sulfide and
fipronil desulfinyl. Among the triad of metabolites, fipronil sulfone exhibits quantitatively …

[HTML][HTML] Effects of pesticide intake on gut microbiota and metabolites in healthy adults

J Ueyama, M Hayashi, M Hirayama… - International Journal of …, 2022 - mdpi.com
Animal experiments have indicated that pesticides may affect gut microbiota, which is
responsible for the production of short-chain fatty acids (SCFAs) and polyamines. Here, we …

[HTML][HTML] Ambient long-term exposure to organophosphorus pesticides and the human gut microbiome: an observational study

K Zhang, K Paul, JP Jacobs, MG Cockburn… - Environmental …, 2024 - Springer
Background Organophosphorus pesticides (OP) have been associated with various human
health conditions. Animal experiments and in-vitro models suggested that OP may also …