Do hormone‐modulating chemicals impact on reproduction and development of wild amphibians?

F Orton, CR Tyler - Biological Reviews, 2015 - Wiley Online Library
Globally, amphibians are undergoing a precipitous decline. At the last estimate in 2004,
32% of the approximately 6000 species were threatened with extinction and 43% were …

Toxicity of organotin compounds: shared and unshared biochemical targets and mechanisms in animal cells

A Pagliarani, S Nesci, V Ventrella - Toxicology in Vitro, 2013 - Elsevier
Most biochemical effects of organotin compounds leading to toxicity are astonishingly similar
in different animal species. In vitro tests, designed to explore organotin action modes at cell …

The obesogen tributyltin induces abnormal ovarian adipogenesis in adult female rats

JFP de Araújo, PL Podratz, GC Sena, E Merlo… - Toxicology Letters, 2018 - Elsevier
Tributyltin chloride (TBT) is an obesogen associated with various metabolic and
reproductive dysfunctions after in utero exposure. However, few studies have evaluated …

Alternatives to in vivo tests to detect endocrine disrupting chemicals (EDCs) in fish and amphibians – screening for estrogen, androgen and thyroid hormone …

S Scholz, P Renner, SE Belanger… - Critical Reviews in …, 2013 - Taylor & Francis
Endocrine disruption is considered a highly relevant hazard for environmental risk
assessment of chemicals, plant protection products, biocides and pharmaceuticals …

Environmental remediation techniques of tributyltin contamination in soil and water: A review

J Du, S Chadalavada, Z Chen, R Naidu - Chemical Engineering Journal, 2014 - Elsevier
Tributyltin (TBT) compounds are active constituents of organotin antifouling paints which
were used to prevent the growth of 'fouling'organisms on marine structures and vessels …

Effects of estrogens and antiestrogens on gonadal sex differentiation and embryonic development in the domestic fowl (Gallus gallus domesticus)

L Jessl, R Lenz, FG Massing, J Scheider, J Oehlmann - PeerJ, 2018 - peerj.com
Since it is known that environmental contaminants have the potential to cause endocrine
disorders in humans and animals, there is an urgent need for in vivo tests to assess possible …

Subchronic and low dose of tributyltin exposure leads to reduced ovarian reserve, reduced uterine gland number, and other reproductive irregularities in female mice

IV Sarmento, E Merlo, SS Meyrelles… - Toxicological …, 2020 - academic.oup.com
Tributyltin (TBT) chloride is an endocrine disrupting chemical associated with reproductive
complications. Studies have shown that TBT targets the reproductive tract, impairing ovarian …

[HTML][HTML] Morphological and transcriptomic effects of endocrine modulators on the gonadal differentiation of chicken embryos: the case of tributyltin (TBT)

J Scheider, F Afonso-Grunz, L Jessl, K Hoffmeier… - Toxicology Letters, 2018 - Elsevier
Morphological malformations induced by tributyltin (TBT) exposure during embryonic
development have already been characterized in various taxonomic groups, but …

Screening of ovarian steroidogenic pathway in Ciona intestinalis and its modulation after tributyltin exposure

MV Cangialosi, E Puccia, A Mazzola… - Toxicology and applied …, 2010 - Elsevier
In this study, we have identified several ovarian steroids in Ciona with high similarity to
vertebrate steroids and showed that cholesterol, corticosterone, dehydroepiandrosterone …

Dibutyltin (DBT) inhibits in vitro androgen biosynthesis of rat immature Leydig cells

G Li, X Chang, Y Zhao, D Li, X Kang - Toxicology, 2021 - Elsevier
Dibutyltin (DBT) is an organotine widely applied in stabilizing plastics and de-worm poultry
agents. But the effects of DBT on immature Leydig cells remain elusive. Thus, the present …