Plus-strand (+) RNA viruses co-opt host RNA-binding proteins (RBPs) to perform many
functions during viral replication. A few host RBPs have been identified that affect the …

Hfq and other Sm proteins are central in RNA metabolism, forming an evolutionarily
conserved family that plays key roles in RNA processing in organisms ranging from archaea …

SMN1, the causative gene for spinal muscular atrophy (SMA), plays a housekeeping role in
the biogenesis of small nuclear RNA ribonucleoproteins. SMN is also present in granular …

Eukaryotic cells contain numerous membraneless organelles that are made from liquid
droplets of proteins and nucleic acids and that provide spatiotemporal control of various …

In nature, stressful environments often occur in combination or close succession, and thus
the ability to prepare for impending stress likely provides a significant fitness advantage …

Abstract The highly conserved 5'–3'exonuclease Xrn1 regulates gene expression in
eukaryotes by coupling nuclear DNA transcription to cytosolic mRNA decay. By integrating …

Assembly of viral replicase complexes of eukaryotic positive-strand RNA viruses is a
regulated process: multiple viral and host components must be assembled on intracellular …

Host factors play crucial roles in the replication of plus-strand RNA viruses. In this report, a
heat shock protein 90 homologue of Nicotiana benthamiana, NbHsp90, was identified in …

Plant viruses are important pathogens that cause serious crop losses worldwide. They are
obligate intracellular parasites that commandeer a wide array of proteins, as well as …

Plants evolved several mechanisms to protect themselves against viruses. Besides
recessive resistance, where compatible host factors required for viral proliferation are absent …