Next-generation sequencing (NGS) technology has expanded in the last decades with
significant improvements in the reliability, sequencing chemistry, pipeline analyses, data …

Technological advances have led to the introduction of next-generation sequencing (NGS)
platforms in cancer investigation. NGS allows massive parallel sequencing that affords …

Context.—In 2013, an evidence-based guideline was published by the College of American
Pathologists, the International Association for the Study of Lung Cancer, and the Association …

Intraductal neoplasms are important precursors to invasive pancreatic cancer and provide
an opportunity to detect and treat pancreatic neoplasia before an invasive carcinoma …

One-hundred-fifty-three biliary cancers, including 70 intrahepatic cholangiocarcinomas
(ICC), 57 extrahepatic cholangiocarcinomas (ECC) and 26 gallbladder carcinomas (GBC) …

Lung cancer is the leading cause of cancer-related deaths worldwide. Despite
advancements and improvements in surgical and medical treatments, the survival rate of …

Context.—As our understanding of genomic alterations underlying solid tumor malignancies
continues to evolve, molecular testing of tumor samples is increasingly used to guide …

The diagnostic work-up for non-small cell lung cancer (NSCLC) requires biomarker testing
to guide therapy choices. This article is the second of a two-part series. In Part 1, we …

Background: Mixed adenoneuroendocrine carcinomas (MANECs) of the gastrointestinal
tract are rare neoplasms characterized by coexisting exocrine and neuroendocrine …

The advent of targeted therapy in lung cancer has heralded a paradigm shift in the practice
of cytopathology with the need for accurately subtyping lung carcinoma, as well as providing …