Neuroimmune axes of the blood–brain barriers and blood–brain interfaces: bases for physiological regulation, disease states, and pharmacological interventions
MA Erickson, WA Banks - Pharmacological reviews, 2018 - ASPET
Central nervous system (CNS) barriers predominantly mediate the immune-privileged status
of the brain, and are also important regulators of neuroimmune communication. It is …
of the brain, and are also important regulators of neuroimmune communication. It is …
The blood–brain barrier and immune function and dysfunction
WA Banks, MA Erickson - Neurobiology of disease, 2010 - Elsevier
The blood–brain barrier (BBB) is the monocellular interface that divides the peripheral
circulation from direct contact with the central nervous system (CNS). This interface consists …
circulation from direct contact with the central nervous system (CNS). This interface consists …
Transport of extracellular vesicles across the blood-brain barrier: brain pharmacokinetics and effects of inflammation
Extracellular vesicles can cross the blood–brain barrier (BBB), but little is known about
passage. Here, we used multiple-time regression analysis to examine the ability of 10 …
passage. Here, we used multiple-time regression analysis to examine the ability of 10 …
Statin therapy and autoimmune disease: from protein prenylation to immunomodulation
Statins have been prescribed extensively for their cholesterol-lowering properties and
efficacy in cardiovascular disease. However, compelling evidence now exists that statins …
efficacy in cardiovascular disease. However, compelling evidence now exists that statins …
Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system
R Cayrol, K Wosik, JL Berard, A Dodelet-Devillers… - Nature …, 2008 - nature.com
Adhesion molecules of the immunoglobulin superfamily are crucial effectors of leukocyte
trafficking into the central nervous system. Using a lipid raft-based proteomic approach, we …
trafficking into the central nervous system. Using a lipid raft-based proteomic approach, we …
leucocyte–endothelial cell crosstalk at the blood–brain barrier: a prerequisite for successful immune cell entry to the brain
J Greenwood, SJ Heasman, JI Alvarez… - Neuropathology and …, 2011 - Wiley Online Library
J. Greenwood, SJ Heasman, JI Alvarez, A. Prat, R. Lyck and B. Engelhardt (2011)
Neuropathology and Applied Neurobiology37, 24–39 Leucocyte–endothelial cell crosstalk …
Neuropathology and Applied Neurobiology37, 24–39 Leucocyte–endothelial cell crosstalk …
Molecular physiology of preconditioning-induced brain tolerance to ischemia
TP Obrenovitch - Physiological reviews, 2008 - journals.physiology.org
Ischemic tolerance describes the adaptive biological response of cells and organs that is
initiated by preconditioning (ie, exposure to stressor of mild severity) and the associated …
initiated by preconditioning (ie, exposure to stressor of mild severity) and the associated …
Neutralization of IL‐17 rescues amyloid‐β‐induced neuroinflammation and memory impairment
C Cristiano, F Volpicelli, P Lippiello… - British journal of …, 2019 - Wiley Online Library
Background and purpose Alzheimer's disease (AD) is a common neurodegenerative
disease characterized by a neuroinflammatory state, and to date, there is no cure and its …
disease characterized by a neuroinflammatory state, and to date, there is no cure and its …
Inflammatory cell migration into the central nervous system: a few new twists on an old tale
S Man, EE Ubogu, RM Ransohoff - Brain pathology, 2007 - Wiley Online Library
Understanding the mechanisms of leukocyte trafficking into the brain might provide insights
into how to modulate pathologic immune responses or enhance host protective mechanisms …
into how to modulate pathologic immune responses or enhance host protective mechanisms …
[HTML][HTML] Integrin targeted delivery of chemotherapeutics
K Chen, X Chen - Theranostics, 2011 - ncbi.nlm.nih.gov
Targeted delivery of chemotherapeutics is defined in the sense, that is, to maximize the
therapeutic index of a chemotherapeutic agent by strictly localizing its pharmacological …
therapeutic index of a chemotherapeutic agent by strictly localizing its pharmacological …