Glioblastoma (GBM) is the most aggressive and deadliest of the primary brain tumors,
characterized by malignant growth, invasion into the brain parenchyma, and resistance to …

Glioblastoma (GBM) is the most common and malignant primary brain tumor in adults.
Currently, the standard treatment of glioblastoma includes surgery, radiotherapy, and …

Clinical treatment of malignant glioma remains a major challenge due to high infiltrative
growth and chemotherapeutic resistance of tumors and the presence of the blood brain …

Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Surgery
followed by chemotherapy and radiotherapy remains the standard treatment strategy for …

Long-term senescent cells exhibit a secretome termed the senescence-associated secretory
phenotype (SASP). Although the mechanisms of SASP factor induction have been …

A remaining challenge in the treatment of glioblastoma multiforme (GBM) is surmounting the
blood–brain barrier (BBB). Such a challenge prevents the development of efficient …

Glioblastoma (GBM), the most common subtype of malignant gliomas, is characterized by
aggressive infiltration, high malignancy, and poor prognosis. The frustrating anti-GBM …

Cancer progression is primarily caused by interactions between transformed cells and the
components of the tumor microenvironment (TME). TAMs (tumor-associated macrophages) …

Exosomes, the cell-derived small extracellular vehicles, play a vital role in intracellular
communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose …

Glioblastoma (GBM) is the most aggressive, malignant primary brain tumor in adults. GBM is
notoriously resistant to immunotherapy mainly due to its unique immune microenvironment …