The chemical constituents and diverse pharmacological importance of Tinospora cordifolia

P Sharma, BP Dwivedee, D Bisht, AK Dash, D Kumar - Heliyon, 2019 - cell.com
Tinospora cordifolia is a popular medicinal plant which is used in several traditional
medicines to cure various diseases. The common names are Amrita and Guduchi and …

Plant immune signaling: Advancing on two frontiers

W Wang, B Feng, JM Zhou… - Journal of integrative plant …, 2020 - Wiley Online Library
Plants have evolved multiple defense strategies to cope with pathogens, among which plant
immune signaling that relies on cell‐surface localized and intracellular receptors takes …

NF‐κB and the link between inflammation and cancer

JA DiDonato, F Mercurio, M Karin - Immunological reviews, 2012 - Wiley Online Library
The nuclear factor‐κB (NF‐κB) transcription factor family has been considered the central
mediator of the inflammatory process and a key participant in innate and adaptive immune …

Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides

T Hander, ÁD Fernández-Fernández, RP Kumpf… - Science, 2019 - science.org
INTRODUCTION Cellular damage caused by wounding triggers signals to alert the
surrounding tissue. As a universal process in all multicellular organisms, these signals …

Inflammation meets cancer, with NF-κB as the matchmaker

Y Ben-Neriah, M Karin - Nature immunology, 2011 - nature.com
Inflammation is a fundamental protective response that sometimes goes awry and becomes
a major cofactor in the pathogenesis of many chronic human diseases, including cancer …

The evolution of regulated cell death pathways in animals and their evasion by pathogens

B Tummers, DR Green - Physiological reviews, 2022 - journals.physiology.org
The coevolution of host-pathogen interactions underlies many human physiological traits
associated with protection from or susceptibility to infections. Among the mechanisms that …

Programmed cell death in the plant immune system

NS Coll, P Epple, JL Dangl - Cell Death & Differentiation, 2011 - nature.com
Cell death has a central role in innate immune responses in both plants and animals.
Besides sharing striking convergences and similarities in the overall evolutionary …

The sequence of the human genome

JC Venter, MD Adams, EW Myers, PW Li, RJ Mural… - science, 2001 - science.org
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human
genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion …

Analysis of the genome sequence of the flowering plant Arabidopsis thaliana

… genomeanalysis@ tgr. org genomeanalysis@ gsf. de - nature, 2000 - nature.com
The flowering plant Arabidopsis thaliana is an important model system for identifying genes
and determining their functions. Here we report the analysis of the genomic sequence of …

[HTML][HTML] Missing pieces in the NF-κB puzzle

S Ghosh, M Karin - cell, 2002 - cell.com
The regulation of the transcription factor NF-κB activity occurs at several levels including
controlled cytoplasmic-nuclear shuttling and modulation of its transcriptional activity. A …