No other tissue in the body depends more on the composition and organization of the
extracellular matrix (ECM) for normal structure and function than the corneal stroma. The …

Gelatin has been used for many years in pharmaceutical formulation, cell culture and tissue
engineering on account of its excellent biocompatibility, ease of processing and availability …

Purpose Single cell (sc) analyses of key embryonic, fetal and adult stages were performed to
generate a comprehensive single cell atlas of all the corneal and adjacent conjunctival cell …

Mesenchymal stem cells from corneal stromal stem cells (CSSC) prevent fibrotic scarring
and stimulate regeneration of transparent stromal tissue after corneal wounding in mice …

To address the growing need for corneal transplants two main approaches are being
pursued: allogenic and synthetic materials. Allogenic tissue from human donors is currently …

Conventional allograft therapy for corneal scarring is widespread and successful, but donor
tissue is not universally available, and some grafts fail owing to rejection and complications …

Acute ocular chemical burns are ophthalmic emergencies requiring immediate diagnosis
and treatment as they may lead to permanent impairment of vision. The clinical …

Aniridia, a rare congenital disease, is often characterized by a progressive, pronounced
limbal insufficiency and ocular surface pathology termed aniridia-associated keratopathy …

Telocytes (TC s) are a distinct type of interstitial cells characterized by a small cell body and
extremely long and thin telopodes (Tps). The presence of TC s has been documented in …

Corneal blindness is traditionally treated by transplantation of a donor cornea, or in severe
cases by implantation of an artificial cornea or keratoprosthesis. Due to severe donor …