Divergent syntheses of complex Veratrum alkaloids

Y Guo, R Fang, Y Jiao, J Liu, JT Lu, T Luo - Nature Communications, 2024 - nature.com
The Veratrum alkaloids are a class of highly intricate natural products renowned for their
complex structural and stereochemical characteristics, which underlie a diverse array of …

[HTML][HTML] Honeybee CaV4 has distinct permeation, inactivation, and pharmacology from homologous NaV channels

A Bertaud, T Cens, A Chavanieu, S Estaran… - Journal of General …, 2024 - rupress.org
DSC1, a Drosophila channel with sequence similarity to the voltage-gated sodium channel
(NaV), was identified over 20 years ago. This channel was suspected to function as a non …

New insights into cardiac ion channel regulation 2.0

BP Delisle, AS Aromolaran - International Journal of Molecular Sciences, 2023 - mdpi.com
Sudden cardiac death (SCD) and arrhythmias represent a global public health problem,
accounting for 15–20% of all deaths [1, 2]. The past 30 years have seen improvements in …

[HTML][HTML] Insecticidal Agents in Pest Control: Sources, Challenges, and Advantages

SK Okwute, HO Egharevba - 2024 - intechopen.com
Insect pests are found commonly in two critical areas of human life: the farms and crop
storage facilities and the home, where they cause a number of problems, including the …

Inhibitory Effects of Nobiletin on Voltage-Gated Na+ Channel in Rat Ventricular Myocytes Based on Electrophysiological Analysis and Molecular Docking Method

Y Gu, J Wang, M Li, F Zhong, J Xiang, Z Xu - International Journal of …, 2022 - mdpi.com
Nobiletin (NOB) has attracted much attention owing to its outstanding bioactivities. This
study aimed to investigate its anti-arrhythmic effect through electrophysiological and …