Simple Summary The use of biomarkers can provide information about the outcome of
cancer patients, the type of tumor, its malignant potential and the risk of recurrence, and may …

This review focuses on the regulation and modulation of human DNA polymerase δ (Pol δ).
The emphasis is on the mechanisms that regulate the activity and properties of Pol δ in DNA …

Cells respond to cytotoxic DNA double-strand breaks (DSBs) by recruiting DNA repair
proteins to the damaged site. This recruitment is dependent on ubiquitylation of adjacent …

Circular RNAs (circRNAs) are a type of endogenous non-coding RNAs, which have been
considered to mediate diverse tumorigenesis including angiogenesis. The present study …

Alzheimer's disease (AD) is characterized by the presence of β-amyloid plaques (Aβ) and
neurofibrillary tangles (NFTs) in the brain. The prevalence of the disease is increasing and is …

Background Ribosomes, the organelles responsible for the translation of mRNA, are
comprised of four rRNAs and~ 80 ribosomal proteins (RPs). Although canonically assumed …

Background Increased tissue stiffness is a common feature of malignant solid tumors, often
associated with metastasis and poor patient outcomes. Vitronectin, as an extracellular matrix …

FOXP2, a member of forkhead box transcription factor family, was first identified as a
language-related gene that played an important role in language learning and facial …

Glioblastoma (GBM) is the most malignant tumor in the central nervous system and the
treatment is still unsatisfactory because the mechanism of the disease remains unclear. The …

Ribosomes coordinate spatiotemporal control of gene expression, contributing to the
acquisition and maintenance of cancer phenotype. The link between ribosomes and cancer …