[HTML][HTML] Neurotransmitters—key factors in neurological and neurodegenerative disorders of the central nervous system

RI Teleanu, AG Niculescu, E Roza… - International journal of …, 2022 - mdpi.com
Neurotransmitters are molecules that amplify, transmit, and convert signals in cells, having
an essential role in information transmission throughout the nervous system. Hundreds of …

Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

[HTML][HTML] The neuroprotective effects of glucagon-like peptide 1 in Alzheimer's and Parkinson's disease: An in-depth review

N Reich, C Hölscher - Frontiers in neuroscience, 2022 - frontiersin.org
Currently, there is no disease-modifying treatment available for Alzheimer's and Parkinson's
disease (AD and PD) and that includes the highly controversial approval of the Aβ-targeting …

Protective properties of GLP‐1 and associated peptide hormones in neurodegenerative disorders

C Hölscher - British journal of pharmacology, 2022 - Wiley Online Library
Type 2 diabetes mellitus and the associated desensitisation of insulin signalling has been
identified as a risk factor for progressive neurodegenerative disorders such as Alzheimer's …

[HTML][HTML] Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in …

L Wang, J Ding, C Zhu, B Guo… - International …, 2021 - spandidos-publications.com
Epilepsy comorbidities and anti‑epileptic drugs (AEDs) are currently the main limitations of
epilepsy treatment. Semaglutide is a glucagon like peptide‑1 analogue that has entered the …

Hydrophilic interaction chromatography combined with ultrasound-assisted ionic liquid dispersive liquid–liquid microextraction for determination of underivatized …

GS Zhou, YC Yuan, Y Yin, YP Tang, RJ Xu, Y Liu… - Analytica chimica …, 2020 - Elsevier
A sensitive, rapid, precise and specific analytical method of hydrophilic interaction ultra-
performance liquid chromatography coupled with triple-quadrupole linear ion-trap tandem …

Therapeutic application of GLP-1 and GIP receptor agonists in Parkinson's disease

X Yang, P Feng, R Ji, Y Ren, W Wei… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Diabetes is a risk factor for Parkinson's disease (PD) and shares similar
dysregulated insulin pathways. Glucagon-like peptide-1 (GLP-1) analogs originally …

[HTML][HTML] Effect of semaglutide and empagliflozin on cognitive function and hippocampal phosphoproteomic in obese mice

X Chen, S Chen, Z Li, R Zhu, Z Jia, J Ban… - Frontiers in …, 2023 - frontiersin.org
Objective: Based on the 4D label-free phosphoproteomic technique, we examined the
differences in cognitive function and hippocampal phosphorylated protein expression in …

[HTML][HTML] Magnetite nanoparticles functionalized with therapeutic agents for enhanced ENT antimicrobial properties

M Caciandone, AG Niculescu, V Grumezescu, AC Bîrcă… - Antibiotics, 2022 - mdpi.com
In the context of inefficient antibiotics, antibacterial alternatives are urgently needed to stop
the increasing resistance rates in pathogens. This study reports the fabrication and …

[HTML][HTML] Exendin-4 promotes retinal ganglion cell survival and function by inhibiting calcium channels in experimental diabetes

YC Wang, L Wang, YQ Shao, SJ Weng, XL Yang… - Iscience, 2023 - cell.com
Progressive damage of retinal ganglion cells (RGCs) is observed in early diabetic
retinopathy. Intracellular Ca 2+ overload mediated by Ca 2+ influx through voltage-gated Ca …