Most of us live blissfully unaware of the orchestrated function that our internal organs
conduct. When this peace is interrupted, it is often by routine sensations of hunger and urge …

Inflammatory diseases have become increasingly prevalent with industrialization. To
address this, numerous anti-inflammatory agents and molecular targets have been …

Up to 20% of people worldwide develop gastrointestinal symptoms following a meal, leading
to decreased quality of life, substantial morbidity and high medical costs. Although the …

Carbon quantum dots (CQDs) are extensively applied for bioimaging due to their unique
photoluminescence properties, while less attention has been paid to their inherent bio …

Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder that is
characterized by abdominal pain and an altered defecation pattern. It affects between 5 and …

Intestinal proteases mediate digestion and immune signalling, while increased gut
proteolytic activity disrupts the intestinal barrier and generates visceral hypersensitivity …

Functional gastrointestinal disorders—recently renamed into disorders of gut–brain
interaction—such as irritable bowel syndrome and functional dyspepsia are highly prevalent …

Inflammatory Bowel Diseases (IBD) are chronic inflammatory disorders, where epithelial
defects drive, at least in part, some of the pathology. We reconstituted human intestinal …

Auch wurden ähnlich wie bei der Vorgängerleitlinie die Empfehlungen zum kindlichen
Reizdarmsyndrom und Empfehlungen zur Abgrenzung intestinaler Motilitätsstörungen …

Once activated at the surface of cells, G protein-coupled receptors (GPCRs) redistribute to
endosomes, where they can continue to signal. Whether GPCRs in endosomes generate …