Short-T2 MRI: Principles and recent advances

M Weiger, KP Pruessmann - Progress in nuclear magnetic resonance …, 2019 - Elsevier
Among current modalities of biomedical and diagnostic imaging, MRI stands out by virtue of
its versatile contrast obtained without ionizing radiation. However, in various cases, eg …

Towards quantification of myelin by solid-state MRI of the lipid matrix protons

AC Seifert, C Li, MJ Wilhelm, SL Wehrli, FW Wehrli - NeuroImage, 2017 - Elsevier
Purpose Direct assessment of myelin has the potential to reveal central nervous system
abnormalities and serve as a means to follow patients with demyelinating disorders during …

Feasibility of assessing bone matrix and mineral properties in vivo by combined solid-state 1H and 31P MRI

X Zhao, HK Song, AC Seifert, C Li, FW Wehrli - PLoS One, 2017 - journals.plos.org
Purpose To develop and evaluate an integrated imaging protocol for bone water and
phosphorus quantification in vivo by solid-state 1H and 31P MRI. Materials and methods All …

Quantitative 31P magnetic resonance imaging on pathologic rat bones by ZTE at 7T

VB Kassey, M Walle, J Egan, D Yeritsyan, I Beeram… - Bone, 2024 - Elsevier
Background Osteoporosis is characterized by low bone mineral density (BMD), which
predisposes individuals to frequent fragility fractures. Quantitative BMD measurements can …

Bone mineral 31P and matrix‐bound water densities measured by solid‐state 31P and 1H MRI

AC Seifert, C Li, CS Rajapakse… - NMR in …, 2014 - Wiley Online Library
Bone is a composite material consisting of mineral and hydrated collagen fractions. MRI of
bone is challenging because of extremely short transverse relaxation times, but solid‐state …

Correction of excitation profile in zero echo time (ZTE) imaging using quadratic phase-modulated RF pulse excitation and iterative reconstruction

C Li, JF Magland, AC Seifert… - IEEE transactions on …, 2014 - ieeexplore.ieee.org
Zero-echo Time (ZTE) imaging is a promising technique for magnetic resonance imaging
(MRI) of short-T2 tissue nuclei in tissues. A problem inherent to the method currently …

Selective in vivo bone imaging with long‐T2 suppressed PETRA MRI

C Li, JF Magland, X Zhao, AC Seifert… - Magnetic Resonance …, 2017 - Wiley Online Library
Purpose To design and evaluate an optimized PETRA (point‐wise encoding time reduction
with radial acquisition) sequence with long‐T2 suppression at 3 Tesla. Methods An …

A Surrogate Measure of Cortical Bone Matrix Density by Long T2‐Suppressed MRI

AC Seifert, C Li, SL Wehrli… - Journal of Bone and …, 2015 - academic.oup.com
Magnetic resonance has the potential to image and quantify two pools of water within bone:
free water within the Haversian pore system (transverse relaxation time, T2> 1 ms), and …

Unraveling Water-Mediated 31P Relaxation in Bone Mineral

N Dwivedi, R Dubey, S Srivastava, N Sinha - ACS omega, 2022 - ACS Publications
Bone is a dynamic tissue composed of organic proteins (mainly type I collagen), inorganic
components (hydroxyapatite), lipids, and water that undergoes a continuous rebuilding …

Solid-state 31P and 1H chemical MR micro-imaging of hard tissues and biomaterials with magic angle spinning at very high magnetic field

M Yon, V Sarou-Kanian, U Scheler, JM Bouler… - Scientific Reports, 2017 - nature.com
In this work, we show that it is possible to overcome the limitations of solid-state MRI for rigid
tissues due to large line broadening and short dephasing times by combining Magic Angle …