Quantifying fat replacement of muscle by quantitative MRI in muscular dystrophy

J Burakiewicz, CDJ Sinclair, D Fischer, GA Walter… - Journal of …, 2017 - Springer
The muscular dystrophies are rare orphan diseases, characterized by progressive muscle
weakness: the most common and well known is Duchenne muscular dystrophy which affects …

[HTML][HTML] Magnetic resonance imaging techniques for the quantitative analysis of skeletal muscle: state of the art

K Engelke, O Chaudry, L Gast, MAB Eldib… - Journal of Orthopaedic …, 2023 - Elsevier
Background Magnetic resonance imaging (MRI) is the dominant 3D imaging modality to
quantify muscle properties in skeletal muscle disorders, in inherited and acquired muscle …

Treatment of sarcopenia with bimagrumab: results from a phase II, randomized, controlled, proof‐of‐concept study

D Rooks, J Praestgaard, S Hariry… - Journal of the …, 2017 - Wiley Online Library
Objectives To assess the effects of bimagrumab on skeletal muscle mass and function in
older adults with sarcopenia and mobility limitations. Design A 24‐week, randomized …

Improving object detection with deep convolutional networks via bayesian optimization and structured prediction

Y Zhang, K Sohn, R Villegas… - Proceedings of the …, 2015 - openaccess.thecvf.com
Object detection systems based on the deep convolutional neural network (CNN) have
recently made ground-breaking advances on several object detection benchmarks. While …

Feasibility of MR-based body composition analysis in large scale population studies

J West, O Dahlqvist Leinhard, T Romu, R Collins… - PloS one, 2016 - journals.plos.org
Introduction Quantitative and accurate measurements of fat and muscle in the body are
important for prevention and diagnosis of diseases related to obesity and muscle …

Activin type II receptor blockade for treatment of muscle depletion in chronic obstructive pulmonary disease. A randomized trial

MI Polkey, J Praestgaard, A Berwick… - American journal of …, 2019 - atsjournals.org
Rationale: Bimagrumab is a fully human monoclonal antibody that blocks the activin type II
receptors, preventing the activity of myostatin and other negative skeletal muscle regulators …

Automated analysis of liver fat, muscle and adipose tissue distribution from CT suitable for large-scale studies

J Kullberg, A Hedström, J Brandberg, R Strand… - Scientific reports, 2017 - nature.com
Computed Tomography (CT) allows detailed studies of body composition and its association
with metabolic and cardiovascular disease. The purpose of this work was to develop and …

Characterization of the regional distribution of skeletal muscle adipose tissue in type 2 diabetes using chemical shift‐based water/fat separation

DC Karampinos, T Baum, L Nardo… - Journal of Magnetic …, 2012 - Wiley Online Library
Purpose: To show the feasibility of assessing the spatial distribution of skeletal muscle
adipose tissue using chemical shift‐based water/fat separation and to characterize …

Segmentation and quantification of adipose tissue by magnetic resonance imaging

HH Hu, J Chen, W Shen - … Resonance Materials in Physics, Biology and …, 2016 - Springer
In this brief review, introductory concepts in animal and human adipose tissue segmentation
using proton magnetic resonance imaging (MRI) and computed tomography are …

The advantages and limitations of cross-sectional body composition analysis

AJ MacDonald, CA Greig… - Current opinion in …, 2011 - journals.lww.com
CS imaging can reliably measure muscle and fat distribution and uniquely discriminate
between intra-abdominal organ and muscle component of fat-free mass. It precisely tracks …