Reactive oxygen species (ROS) are important signaling molecules in cancer. The level of
ROS will determine physiological effects. While high levels of ROS can cause damage to …

Myofibroblasts are contractile, α-smooth muscle actin-positive cells with multiple roles in
pathophysiological processes. Myofibroblasts mediate wound contractions, but their …

The communication between tumor-derived elements and stroma in the metastatic niche has
a critical role in facilitating cancer metastasis. Yet, the mechanisms tumor cells use to control …

Massive bleeding and wound infection after tissue trauma are the major dangerous factors
of casualties in disasters; hence, first‐aid supplies that can greatly achieve wound closure …

Background Hepatocellular carcinoma (HCC) remains a global challenge due to its high
morbidity and mortality rates as well as poor response to treatment. The communication …

The epithelial-mesenchymal transition (EMT) describes the global process by which
stationary epithelial cells undergo phenotypic changes, including the loss of cell-cell …

Ovarian cancer is the most lethal gynecological malignancy. It is usually diagnosed at a late
stage, with a 5-yr survival rate of< 30%. The majority of ovarian cancer cases are diagnosed …

Significance: Scarring of the skin from burns, surgery, and injury constitutes a major burden
on the healthcare system. Patients affected by major scars, particularly children, suffer from …

Neoplastic cells recruit fibroblasts through various growth factors and cytokines. These
“cancer-associated fibroblasts”(CAF) actively interact with neoplastic cells and form a …

Much interest is currently focused on the emerging role of tumor-stroma interactions
essential for supporting tumor progression. Carcinoma-associated fibroblasts (CAFs) …