The reactivity of the N-Boc protecting group: an underrated feature

C Agami, F Couty - Tetrahedron, 2002 - Elsevier
Among the large array of protecting groups, the tert-butoxycarbonyl (Boc) substituent is
considered to be one of the most useful. In particular, it has gained an indisputable …

New hybrid transition state analog inhibitors of HIV protease with peripheric C2-symmetry

B Stowasser, KH Budt, L Jian-Qi, A Peyman… - Tetrahedron letters, 1992 - Elsevier
The snythesis of novel hybrid transition state analogs, a combination of phosphinic acid-and
hydroxy-methylene-type inhibitors of HIV protease, is demonstrated. These nonsymmetrical …

Oxazolidin-2-one ring, a popular framework in synthetic organic chemistry: Part 1. The construction of the oxazolidin-2-one ring

G Zappia, E Gacs-Baitz… - Current Organic …, 2007 - ingentaconnect.com
The 1, 3-oxazolidin-2-one nucleus is a popular heterocycle framework in synthetic organic
chemistry, as well as in medicinal chemistry. This paper deals with the huge number of …

Ready access to stereodefined β-hydroxy-γ-amino acids. Enantioselective synthesis of fully protected cyclohexylstatine

P Castejón, A Moyano, MA Pericàs, A Riera - Tetrahedron, 1996 - Elsevier
A convenient entry to enantiopure syn or anti β-hydroxy-γ-amino acids is described. The
starting compounds for the synthesis, anti 3-amino-1, 2-diols, are readily available in high …

Practical Asymmetric Approach to Pyrrolidinones: Efficient Synthesis of (+)-Preussin and (−)-AHPPA

A Kanazawa, S Gillet, P Delair… - The Journal of Organic …, 1998 - ACS Publications
A novel, dichloroketene− chiral enol ether cycloaddition-based synthesis of enantiopure (+)-
preussin and (−)-AHPPA has been realized. The efficient, highly stereoselective approach …

Stereoselective intramolecular cyclization of allyl and homoallyl benzamide via π-allylpalladium complex catalyzed by Pd (0)

KY Lee, YH Kim, MS Park, CY Oh… - The Journal of organic …, 1999 - ACS Publications
The transformation of acyclic allylic benzamides 4 and homoallylic benzamides 12 to vinyl
oxazolines 3 is achieved in the presence of base by the catalysis of Pd (0) in high yield and …

Stereoselective hydrogen transfer reactions involving acyclic radicals. Tandem substituted tetrahydrofuran formation and stereoselective reduction: synthesis of the …

Y Guindon, C Yoakim, V Gorys… - The Journal of …, 1994 - ACS Publications
The tandem iodoetherification reaction and stereoselective reduction of acyclic radicals has
been used in the stereocontroUed synthesis of substituted tetrahydrofurans. Such a …

Chiral synthons for 2-amino alcohols. Facile preparation of optically active amino hydroxy acids of biological interest.

T Ishizuka, S Ishibuchi, T Kunieda - Tetrahedron, 1993 - Elsevier
A promising method for the versatile synthesis of chiral 2-amino alcohols is provided by the
enantioselective functionalization of the olefinic moiety of the simple heterocycle, 2 …

The N-Hydroxymethyl Group for Stereoselective Conjugate Addition:  Application to the Synthesis of (−)-Statine

D Yoo, JS Oh, YG Kim - Organic Letters, 2002 - ACS Publications
The N-Hydroxymethyl Group for Stereoselective Conjugate Addition: Application to the
Synthesis of (−)-Statine | Organic Letters ACS ACS Publications C&EN CAS Find my institution …

Cyclofunctionalization and Free-Radical-Based Hydrogen-Transfer Reactions. An Iterative Reaction Sequence Applied to the Synthesis of the C7−C16 Subunit of …

Y Guindon, L Murtagh, V Caron… - The Journal of …, 2001 - ACS Publications
The strategy considered herein features an iodocyclofunctionalization/hydrogen-transfer
reaction sequence for the elaboration of propionate motifs. Proceeding with excellent yield …