Most neurodegenerative diseases are characterized by intracellular aggregates of insoluble
proteins. As for the majority of these disorders, aetiology and pathogenesis are only poorly …

Mammals have evolved a range of behavioural and neurological mechanisms that
coordinate cycles of thermoregulation and sleep. Whether diurnal or nocturnal, sleep onset …

Carey, Hannah V., Matthew T. Andrews, and Sandra L. Martin. Mammalian Hibernation:
Cellular and Molecular Responses to Depressed Metabolism and Low Temperature. Physiol …

The energy allocation (EA) model defines behavioral strategies that optimize the temporal
utilization of energy to maximize reproductive success. This model proposes that all species …

Core body temperature is normally tightly regulated to within a few tenths of a degree. The
major thermoregulatory defences in humans are sweating, arteriovenous shunt …

The last 'hibernation book'was published in 1982, nearly 40 years ago, so clearly an update
was needed. The options were a book written by a single author or an edited book written by …

Hibernation is widely regarded as an adaptation to seasonal energy shortage, but the actual
influence of energy availability on hibernation patterns is rarely considered. Here we review …

Phylogenetic and ontogenetic associations between sleep and endothermy are consistent
with the hypothesis that sleep evolved in conjuction with endothermy to offset the high …

Thriving in times of resource scarcity requires an incredible flexibility of behavioral,
physiological, cellular, and molecular functions that must change within a relatively short …

Neurofibrillary pathology [paired helical filaments (PHFs)] formed by the microtubule-
associated protein tau in a hyperphosphorylated form is a major hallmark of Alzheimer's …