Abstract Purpose of Review Neuroinflammation plays a significant role in Parkinson's
disease (PD) etiology along with mitochondrial dysfunction and impaired proteostasis. In this …

Parkinson's disease (PD) is the second most common neurodegenerative disease which
significantly influences the life quality of patients. The protein α-synuclein plays an important …

Parkinson's disease (PD) is a progressive neurodegenerative disorder affecting millions of
people worldwide. Mutations in the gene encoding leucine-rich repeat kinase 2 (LRRK2) are …

Parkinson's Disease (PD) affects millions of people worldwide with no cure to halt the
progress of the disease. Leucine-rich repeat kinase 2 (LRRK2) is the most common genetic …

The major breakthroughs in our knowledge of how biology plays a role in Parkinson's
disease (PD) have opened up fresh avenues designed to know the pathogenesis of disease …

Abstract Mutations in the Leucine-Rich Repeat Kinase 2 (LRRK2) gene are associated with
familial and sporadic cases of Parkinson's disease (PD) but are also found in patients with …

Inflammation is a natural host defense mechanism that protects the body from pathogenic
microorganisms. A growing body of research suggests that inflammation is a key factor in …

Parkinson's disease (PD) is a prevalent neurodegenerative disorder that manifests as motor
and nonmotor symptoms due to the selective loss of midbrain DArgic (DA) neurons. More …

Leucine-rich repeat kinase 2 (LRRK2) is a multidomain scaffolding protein with dual
guanosine triphosphatase (GTPase) and kinase enzymatic activities, providing this protein …

Parkinson's disease (PD) is increasingly recognised as a systemic disorder in which
inflammation might play a causative role rather than being a consequence or an …