COVID-19, mast cells, cytokine storm, psychological stress, and neuroinflammation
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a new pandemic infectious disease that originated in China …
coronavirus 2 (SARS-CoV-2) is a new pandemic infectious disease that originated in China …
The blood–brain barrier in health and disease
R Daneman - Annals of neurology, 2012 - Wiley Online Library
The blood–brain barrier (BBB) is a term used to describe a series of properties possessed
by the vasculature of the central nervous system (CNS) that tightly regulate the movement of …
by the vasculature of the central nervous system (CNS) that tightly regulate the movement of …
[HTML][HTML] Exosomal miR-155 from M1-polarized macrophages promotes EndoMT and impairs mitochondrial function via activating NF-κB signaling pathway in vascular …
X Ge, P Tang, Y Rong, D Jiang, X Lu, C Ji, J Wang… - Redox biology, 2021 - Elsevier
Abstract Pathologically, blood-spinal-cord-barrier (BSCB) disruption after spinal cord injury
(SCI) leads to infiltration of numerous peripheral macrophages into injured areas and …
(SCI) leads to infiltration of numerous peripheral macrophages into injured areas and …
Blood–brain barrier breakdown as a therapeutic target in traumatic brain injury
Traumatic brain injury (TBI) is the leading cause of death in young adults and children. The
treatment of TBI in the acute phase has improved substantially; however, the prevention and …
treatment of TBI in the acute phase has improved substantially; however, the prevention and …
Blood-brain barrier tight junction permeability and ischemic stroke
KE Sandoval, KA Witt - Neurobiology of disease, 2008 - Elsevier
The blood-brain barrier (BBB) is formed by the endothelial cells of cerebral microvessels,
providing a dynamic interface between the peripheral circulation and the central nervous …
providing a dynamic interface between the peripheral circulation and the central nervous …
Pathways for small molecule delivery to the central nervous system across the blood-brain barrier
JL Mikitsh, AM Chacko - Perspectives in medicinal chemistry, 2014 - journals.sagepub.com
The treatment of central nervous system (CNS) disease has long been difficult due to the
ineffectiveness of drug delivery across the blood-brain barrier (BBB). This review …
ineffectiveness of drug delivery across the blood-brain barrier (BBB). This review …
Transporters at CNS barrier sites: obstacles or opportunities for drug delivery?
L Sanchez-Covarrubias, LM Slosky… - Current …, 2014 - ingentaconnect.com
The blood-brain barrier (BBB) and blood-cerebrospinal fluid (BCSF) barriers are critical
determinants of CNS homeostasis. Additionally, the BBB and BCSF barriers are formidable …
determinants of CNS homeostasis. Additionally, the BBB and BCSF barriers are formidable …
Concussion pathophysiology and injury biomechanics
R Romeu-Mejia, CC Giza, JT Goldman - Current reviews in …, 2019 - Springer
Abstract Purpose of Review The concussion public health burden has increased alongside
our knowledge of the pathophysiology of mild traumatic brain injury (mTBI). The purpose of …
our knowledge of the pathophysiology of mild traumatic brain injury (mTBI). The purpose of …
[HTML][HTML] Blood–brain barrier and gut barrier dysfunction in chronic kidney disease with a focus on circulating biomarkers and tight junction proteins
L Hernandez, LJ Ward, S Arefin, T Ebert… - Scientific reports, 2022 - nature.com
Kidney failure and associated uraemia have implications for the cardiovascular system,
brain, and blood–brain barrier (BBB). We aim to examine BBB disruption, by assessing brain …
brain, and blood–brain barrier (BBB). We aim to examine BBB disruption, by assessing brain …
Pathology and new players in the pathogenesis of brain edema
S Nag, JL Manias, DJ Stewart - Acta neuropathologica, 2009 - Springer
Brain edema continues to be a major cause of mortality after diverse types of brain
pathologies such as major cerebral infarcts, hemorrhages, trauma, infections and tumors …
pathologies such as major cerebral infarcts, hemorrhages, trauma, infections and tumors …