The burden of disease and death attributable to environmental pollution is becoming a
public health challenge worldwide, especially in developing countries. The kidney is …

Aristolochic acid (AA) is a generic term that describes a group of structurally related
compounds found in the Aristolochiaceae plants family. These plants have been used for …

Covering: 1960 to 2013 Aristolochic acids are known for causing aristolochic acid
nephropathy, a renal fibrosis often associated with urothelial carcinoma. Aristolochic acid I …

Autophagy is a dynamic process by which intracellular damaged macromolecules and
organelles are degraded and recycled for the synthesis of new cellular components. Basal …

It has been suggested that autophagy protects renal tubular epithelial cells (TECs) from
injury in diabetic nephropathy (DN). However, the manner in which the autophagy-lysosome …

The use of dietary bioactive compounds in chemoprevention can potentially reverse,
suppress, or even prevent cancer progression. However, the effects of licochalcone A (LicA) …

We previously reported that perfluorooctanesulfonate (PFOS) causes autophagy-induced
apoptosis in renal tubular cells (RTCs) through a mechanism dependent on reactive oxygen …

Air pollution consists of a multi-faceted mix of gases and ambient particulate matter (PM)
with diverse organic and non-organic chemical components that contribute to increasing …

Autophagy is shown to be beneficial for renal tubular injury caused by nephrotoxic drugs. To
investigate whether autophagy could protect renal tubular epithelial cells (TECs) from injury …

Ingestion of aristolochic acids (AAs) contained in herbal remedies results in a renal disease
and, frequently, urothelial malignancy. The genotoxicity of AA in renal cells, including …