[HTML][HTML] Hypoxia-induced PLOD2 promotes clear cell renal cell carcinoma progression via modulating EGFR-dependent AKT pathway activation

T Liu, W Xiang, Z Chen, G Wang, R Cao, F Zhou… - Cell Death & …, 2023 - nature.com
Clear cell renal cell carcinoma (ccRCC) is a type of kidney cancer that is both common and
aggressive, with a rising incidence in recent decades. Hypoxia is a key factor that plays a …

[HTML][HTML] PLOD2 high expression associates with immune infiltration and facilitates cancer progression in osteosarcoma

Z Wang, G Fan, H Zhu, L Yu, D She, Y Wei… - Frontiers in …, 2022 - frontiersin.org
Background Osteosarcoma (OS) is the most common primary malignant bone tumors in
children and adolescents. Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) is a …

[HTML][HTML] Bioinformatics analyses identify the therapeutic potential of ST8SIA6 for colon cancer

CY Ko, TH Chu, CC Hsu, HP Chen, SC Huang… - Journal of Personalized …, 2022 - mdpi.com
Sialylation of glycoproteins is modified by distinct sialyltransferases such as ST3Gal,
ST6Gal, ST6GalNAc, or ST8SIA with α2, 3-, α2, 6-, or α2, 8-linkages. Alteration of these …

[HTML][HTML] DPHL v. 2: An updated and comprehensive DIA pan-human assay library for quantifying more than 14,000 proteins

Z Xue, T Zhu, F Zhang, C Zhang, N Xiang, L Qian, X Yi… - Patterns, 2023 - cell.com
A comprehensive pan-human spectral library is critical for biomarker discovery using mass
spectrometry (MS)-based proteomics. DPHL v. 1, a previous pan-human library built from …

[HTML][HTML] Molecular characterization of colorectal mucinous adenocarcinoma and adenocarcinoma, not otherwise specified, identified by multiomic data analysis

K Xu, S Zheng, B Li, Y Shao, X Yin - Frontiers in Molecular …, 2023 - frontiersin.org
Adenocarcinoma not otherwise specified (AC) and mucinous adenocarcinoma (MC) have
different biological behaviors and clinical features. We utilized our previous proteomic data …

Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 promotes collagen cross-linking and ECM stiffening to induce liver fibrosis

W Yue, H Zhang, Y Gao, J Ding, R Xue, C Dong… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Abstract Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 (Plod2) is a key collagen lysyl
hydroxylase mediating the formation of collagen fiber and stabilized collagen cross-links …

[HTML][HTML] Dysregulation of PLOD2 promotes tumor metastasis and invasion in hepatocellular carcinoma

K Li, Y Niu, K Li, C Zhong, Z Qiu, Y Yuan… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
Methods The Cancer Genome Atlas (TCGA) database and HCC tissue microarrays were
used to evaluate the expression of genes. In vitro migration, invasion, in vivo subcutaneous …

Characterization of Procollagen-lysine, 2-oxoglutarate 5-dioxygenases as Therapeutic Targets in a Pan-Cancer Study

W Liu, J Liu, J Deng, T Zhan, Z Han, J Tan, M Liu… - 2023 - researchsquare.com
Characterization of Procollagen-lysine, 2- oxoglutarate 5-dioxygenases as Therapeutic
Targets in a Pan-Cancer Study Page 1 Page 1/19 Characterization of Procollagen-lysine, 2oxoglutarate …

[PDF][PDF] Defining the role of RhoE/RND3 signalling in the control of skin homeostasis

S Endzhievskaya - 2022 - kclpure.kcl.ac.uk
Dermatofibromas are benign skin growths that can occur at any site on the body and are
characterised by increased levels of extracellular matrix (ECM) proteins. Most …