Activation and regulation of caspase-6 and its role in neurodegenerative diseases
Caspases, a family of cysteine proteases, are major mediators of apoptosis and
inflammation. Caspase-6 is classified as an apoptotic effector, and it mediates nuclear …
inflammation. Caspase-6 is classified as an apoptotic effector, and it mediates nuclear …
Longitudinal four-dimensional mapping of subcortical anatomy in human development
Growing access to large-scale longitudinal structural neuroimaging data has fundamentally
altered our understanding of cortical development en route to human adulthood, with …
altered our understanding of cortical development en route to human adulthood, with …
Longitudinally mapping childhood socioeconomic status associations with cortical and subcortical morphology
Childhood socioeconomic status (SES) impacts cognitive development and mental health,
but its association with human structural brain development is not yet well characterized …
but its association with human structural brain development is not yet well characterized …
Performing label‐fusion‐based segmentation using multiple automatically generated templates
MM Chakravarty, P Steadman… - Human brain …, 2013 - Wiley Online Library
Classically, model‐based segmentation procedures match magnetic resonance imaging
(MRI) volumes to an expertly labeled atlas using nonlinear registration. The accuracy of …
(MRI) volumes to an expertly labeled atlas using nonlinear registration. The accuracy of …
Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus
Early life experience influences stress reactivity and mental health through effects on
cognitive-emotional functions that are, in part, linked to gene expression in the dorsal and …
cognitive-emotional functions that are, in part, linked to gene expression in the dorsal and …
Kctd13 deletion reduces synaptic transmission via increased RhoA
Copy-number variants of chromosome 16 region 16p11. 2 are linked to neuropsychiatric
disorders,,,,, and are among the most prevalent in autism spectrum disorders,,. Of many …
disorders,,,,, and are among the most prevalent in autism spectrum disorders,,. Of many …
Maze training in mice induces MRI-detectable brain shape changes specific to the type of learning
JP Lerch, AP Yiu, A Martinez-Canabal, T Pekar… - Neuroimage, 2011 - Elsevier
Multiple recent human imaging studies have suggested that the structure of the brain can
change with learning. To investigate the mechanism behind such structural plasticity, we …
change with learning. To investigate the mechanism behind such structural plasticity, we …
Morphological alterations in the thalamus, striatum, and pallidum in autism spectrum disorder
M Schuetze, MTM Park, IYK Cho… - …, 2016 - nature.com
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder with cognitive,
motor, and emotional symptoms. The thalamus and basal ganglia form circuits with the …
motor, and emotional symptoms. The thalamus and basal ganglia form circuits with the …
A segmentation protocol and MRI atlas of the C57BL/6J mouse neocortex
The neocortex is the largest component of the mammalian cerebral cortex. It integrates
sensory inputs with experiences and memory to produce sophisticated responses to an …
sensory inputs with experiences and memory to produce sophisticated responses to an …
[HTML][HTML] Magnetic resonance imaging of Huntington's disease: preparing for clinical trials
S Kloeppel, SM Henley, NZ Hobbs, RC Wolf… - Neuroscience, 2009 - Elsevier
The known genetic mutation causing Huntington's disease (HD) makes this disease an
important model to study links between gene and brain function. An autosomal dominant …
important model to study links between gene and brain function. An autosomal dominant …