Background Although great achievements have been made in the field of cancer therapy,
chemotherapy and radiotherapy remain the mainstay cancer therapeutic modalities …

Classical Hodgkin lymphoma is one of the more frequent lymphomas and is generally
considered a highly curable disease with standard first-line chemotherapy and radiotherapy …

Background Survivors of Hodgkin's lymphoma are at increased risk for treatment-related
subsequent malignant neoplasms. The effect of less toxic treatments, introduced in the late …

BACKGROUND Owing to a growing number of young and adolescent Hodgkin lymphoma
(HL) survivors, awareness of (long-term) adverse effects of anticancer treatment increases …

Purpose The risk of breast cancer is high in women treated for a childhood cancer with chest
irradiation. We sought to examine variations in risk resulting from irradiation field and …

Improvements in early detection, supportive care, and treatment have resulted in an
increasing number of cancer survivors, with a current 5-year relative survival rate for all …

Second and higher-order malignancies now comprise about 18% of all incident cancers in
the USA, superseding first primary cancers of the breast, lung, and prostate. The occurrence …

This paper summarizes current knowledge on ionizing radiation-associated breast cancer in
the context of established breast cancer risk factors, the radiation dose–response …

Background Treatment of early-stage Hodgkin's disease is usually tailored in line with
prognostic factors that allow for reductions in the amount of chemotherapy and extent of …

Background Few studies have examined the impact of treatment-related morbidity on long-
term, cause-specific mortality in Hodgkin lymphoma (HL) patients. Methods This multicenter …