The mitochondrial respiratory chain is a major source of reactive oxygen species (ROS) in
eukaryotic cells. Mitochondrial ROS production associated with a dysfunction of respiratory …

Apart from complex I (NADH: ubiquinone oxidoreductase) the mitochondrial cytochrome bc
1 complex (complex III; ubiquinol: cytochrome c oxidoreductase) has been identified as the …

Protein complexes of the mitochondrial respiratory chain assemble into respiratory
supercomplexes. Here we present the high-resolution electron cryo-microscopy structure of …

Atovaquone, a substituted hydroxynaphthoquinone, is a potent antimalarial drug that acts by
inhibiting the parasite's mitochondrial cytochrome bc 1 complex (cyt bc 1). Mutations in cyt …

Aspects of the crystal structures of the hetero-oligomeric cytochrome bc1 and b6f (“bc”)
complexes relevant to their electron/proton transfer function and the associated redox …

Lipids play important roles in cellular dysfunction leading to disease. Although a major role
for phospholipids is in defining the membrane permeability barrier, phospholipids play a …

Increasing cellular damage during the aging process is considered to be one factor limiting
the lifespan of organisms. Besides the DNA and lipids, proteins are frequent targets of non …

Numerous biochemical studies are aimed at elucidating the sources and mechanisms of
formation of reactive oxygen species (ROS) because they are involved in cellular, organ …

I. Введение. II. Кислород как окислитель. III. Митохондрии сердца и их дыхательная
цепь. IV. Объекты и измерение актив ностей мито хондриальных …

Actinobacteria are closely linked to human life as industrial producers of bioactive molecules
and as human pathogens. Respiratory cytochrome bcc complex and cytochrome aa 3 …