Clinical pharmacokinetics of paclitaxel monotherapy: an updated literature review

TB Stage, TK Bergmann, DL Kroetz - Clinical pharmacokinetics, 2018 - Springer
Paclitaxel is an anticancer agent efficacious in the treatment of ovarian, breast, and lung
cancer. Due to a strong link between the pharmacokinetics and therapeutic efficacy of …

Chemical diversity of biologically active metabolites in the sclerotia of Inonotus obliquus and submerged culture strategies for up-regulating their production

W Zheng, K Miao, Y Liu, Y Zhao, M Zhang… - Applied microbiology …, 2010 - Springer
Abstract Inonotus obliquus (Fr.) Pilat is a white rot fungus belonging to the family
Hymenochaetaceae in the Basidiomycota. In nature, this fungus rarely forms a fruiting body …

Phase III study of doxorubicin/cyclophosphamide with concomitant versus sequential docetaxel as adjuvant treatment in patients with human epidermal growth factor …

W Eiermann, T Pienkowski, J Crown… - Journal of clinical …, 2011 - ascopubs.org
Purpose Anthracyclines, taxanes, and alkylating agents are among the most active agents in
treatment of adjuvant breast cancer (BC), but the optimal schedule for their administration is …

Clinical relevance of hepatic and renal P‐gp/BCRP inhibition of drugs: An international transporter consortium perspective

KS Taskar, X Yang, S Neuhoff, M Patel… - Clinical …, 2022 - Wiley Online Library
The role of P‐glycoprotein (P‐gp) and breast cancer resistance protein (BCRP) in drug–drug
interactions (DDIs) and limiting drug absorption as well as restricting the brain penetration of …

Baicalin suppresses lung carcinoma and lung metastasis by SOD mimic and HIF-1α inhibition

G Du, G Han, S Zhang, H Lin, X Wu, M Wang… - European journal of …, 2010 - Elsevier
The dose-related toxicity of anticancer drugs in chemotherapy of clinical carcinoma is the
major obstacle to prolonged survival, we want to investigate selective therapeutic efficacy of …

Cardiotoxicity of doxorubicin/paclitaxel combination in rats: effect of sequence and timing of administration

SY Saad, TAO Najjar, M Alashari - Journal of biochemical and …, 2004 - Wiley Online Library
The higher incidence of cardiotoxicity of doxorubicin (DOX)/paclitaxel (PTX) combination
compared with DOX alone remains to be a major obstacle against effective …

Validated HPLC‐UV Method for Simultaneous Estimation of Paclitaxel and Doxorubicin Employing Ion Pair Chromatography: Application in Formulation Development …

R Saklani, AK Tiwari, PK Yadav… - BioMed Research …, 2022 - Wiley Online Library
Though paclitaxel (PTX) and doxorubicin (DOX) are amongst the most widely used and
investigated drug pair for combination chemotherapy but surprisingly, not a single validated …

A systematic review on drug interactions in oncology

RP Riechelmann, ED Saad - Cancer investigation, 2006 - Taylor & Francis
Objectives: To systematically review drug interactions in oncology. Methods: We searched
PubMed for eligible articles and online databases abstracts of major oncology meetings …

Total flavonoids of Daphne genkwa root significantly inhibit the growth and metastasis of Lewis lung carcinoma in C57BL6 mice

W Zheng, X Gao, C Chen, R Tan - International immunopharmacology, 2007 - Elsevier
Daphne genkwa root has been traditionally used as an effective remedy to treat various
tumors. However, the active constituents for its antitumor potency have not been well …

Индуцированная антрациклинами кардиотоксичность: механизмы развития и клинические проявления

МГ Матяш, ТЛ Кравчук, ВВ Высоцкая… - Сибирский …, 2008 - cyberleninka.ru
В обзоре представлены современные данные об антрациклиновой
кардиотоксичности, механизмах ее развития, предсказывающих факторах, факторах …