The current regenerative medicine approaches of craniofacial diseases: A narrative review

E Tahmasebi, M Mohammadi, M Alam… - Frontiers in Cell and …, 2023 - frontiersin.org
Craniofacial deformities (CFDs) develop following oncological resection, trauma, or
congenital disorders. Trauma is one of the top five causes of death globally, with rates …

Extracellular matrix composition and remodeling: Current perspectives on secondary palate formation, cleft lip/palate, and palatal reconstruction

KBS Paiva, CS Maas, PM Santos… - Frontiers in cell and …, 2019 - frontiersin.org
Craniofacial development comprises a complex process in humans in which failures or
disturbances frequently lead to congenital anomalies. Cleft lip with/without palate (CL/P) is a …

Exploring the potential of hydroxyapatite-based materials in biomedicine: A comprehensive review

C Liu, M Xu, Y Wang, Q Yin, J Hu, H Chen… - Materials Science and …, 2024 - Elsevier
Hydroxyapatite (HA), which shares similarities in both chemical composition and structure
with bone phosphate systems, and has garnered significant attention in biomedicine due to …

Stem cells regenerating the craniofacial skeleton: current state-of-the-art and future directions

JD Oliver, W Madhoun, EM Graham… - Journal of Clinical …, 2020 - mdpi.com
The craniofacial region comprises the most complex and intricate anatomical structures in
the human body. As a result of developmental defects, traumatic injury, or neoplastic tissue …

The use of dual energy X-ray bone density scan in assessment of alveolar cleft grafting using bone marrow stem cells concentrate/platelet-rich fibrin regenerative …

AM Mossaad, HH Al Ahmady… - Journal of …, 2021 - journals.lww.com
Objectives: To determine the densitometric quality of regenerated bone at the site of bone
marrow and platelet-rich membrane grafting technique at unilateral alveolar cleft region …

Long-term treatment outcomes of primary alveolar bone grafts for alveolar clefts: a qualitative systematic review

MK Carbullido, RA Dean, GN Kamel… - The Cleft Palate …, 2022 - journals.sagepub.com
Background: Alveolar bone grafting is utilized to manage alveolar clefts in patients with cleft
lip and palate. However, the timing of bone grafting is variable with conflicting evidence …

Compositions and structural geometries of scaffolds used in the regeneration of cleft palates: A review of the literature

VA Reyna-Urrutia, AM González-González… - Polymers, 2022 - mdpi.com
Cleft palate (CP) is one of the most common birth defects, presenting a multitude of negative
impacts on the health of the patient. It also leads to increased mortality at all stages of life …

Bone growth capacity of human umbilical cord mesenchymal stem cells and BMP-2 seeded into hydroxyapatite/chitosan/gelatin scaffold in alveolar cleft defects: an …

K Bangun, CL Sukasah, IH Dilogo… - The Cleft Palate …, 2021 - journals.sagepub.com
Objective: To evaluate bone regeneration in alveolar defects treated with human umbilical
cord–derived mesenchymal stem cells (hUCMSCs), hydroxyapatite/chitosan/gelatin …

Advanced-platelet-rich fibrin extract promotes adipogenic and osteogenic differentiation of human adipose-derived stem cells in a dose-dependent manner in vitro

Z Liang, D Huang, W Nong, J Mo, D Zhu, M Wang… - Tissue and Cell, 2021 - Elsevier
Advanced platelet-rich fibrin (A-PRF) is an autogenous biological material obtained from
peripheral blood. A-PRF extract (A-PRFe) contains a high concentration of various cytokines …

[HTML][HTML] Use of stem cells in bone regeneration in cleft palate patients: review and recommendations

MA Amiri, F Lavaee… - Journal of the Korean …, 2022 - synapse.koreamed.org
This study was conducted to review the efficacy of different sources of stem cells in bone
regeneration of cleft palate patients. The majority of previous studies focused on the …