Proteins carry out many vital cellular functions determined by their precise 3-dimensional
structures (the native conformations). Understanding how proteins fold has long been a …

Understanding the energetic and structural basis of protein folding in a physiological context
may represent an important step toward the elucidation of protein misfolding and …

This article reports on the interaction of conducting (K+) and blocking (Na+) monovalent
metal ions with detergent-solubilized and lipid-reconstituted forms of the K+ channel KcsA …

Binding of K+ and Na+ to the potassium channel KcsA has been characterized from the
stabilization observed in the heat-induced denaturation of the protein as the ion …

Due to its favorable spectroscopic properties, Cd2+ is frequently used as a probe of Ca2+
sites in proteins. We investigate the ability of Cd2+ to act as a structural and functional …

The pressure effect on conformational equilibria of simple organic compounds and the
pressure denaturation of proteins have been well investigated by using vibrational …

Light absorption by rhodopsin leads to the release of all-trans retinal (ATRal) in the lipid
phase of photoreceptor disc membranes. Retinol dehydrogenase 8 (RDH8) then reduces …

We have investigated the folding of DM43, a homodimeric metalloproteinase inhibitor
isolated from the serum of the South American opossum Didelphis marsupialis …

Visual phototransduction takes place in photoreceptor cells. Light absorption by rhodopsin
leads to the activation of transducin as a result of the exchange of its GDP for GTP. The GTP …

α-Tropomyosin (Tm) is a two-stranded α-helical coiled-coil protein, which participates in the
regulation of muscle contraction. Unlike Tm purified from vertebrate muscle, recombinant Tm …