Transferosomes as a transdermal drug delivery system: Dermal kinetics and recent developments

N Matharoo, H Mohd… - Wiley Interdisciplinary …, 2024 - Wiley Online Library
The development of innovative approaches to deliver medications has been growing now
for the last few decades and generates a growing interest in the dermatopharmaceutical …

Current advances in lipid nanosystems intended for topical and transdermal drug delivery applications

N Akombaetwa, AB Ilangala, L Thom, PB Memvanga… - Pharmaceutics, 2023 - mdpi.com
Skin delivery is an exciting and challenging field. It is a promising approach for effective drug
delivery due to its ease of administration, ease of handling, high flexibility, controlled …

[HTML][HTML] Tip loaded cyclodextrin-carvedilol complexes microarray patches

QK Anjani, AHB Sabri, KA Hamid… - Carbohydrate …, 2023 - Elsevier
Carvedilol, a β-blocker prescribed for chronic heart failure, suffers from poor bioavailability
and rapid first pass metabolism when administered orally. Herein, we present the …

Elastic and ultradeformable liposomes for transdermal delivery of active pharmaceutical ingredients (APIs)

EB Souto, AS Macedo, J Dias-Ferreira, A Cano… - International Journal of …, 2021 - mdpi.com
Administration of active pharmaceutical ingredients (APIs) through the skin, by means of
topical drug delivery systems, is an advanced therapeutic approach. As the skin is the …

Lipid-based nanovesicular drug delivery systems

T Limongi, F Susa, M Marini, M Allione, B Torre… - Nanomaterials, 2021 - mdpi.com
In designing a new drug, considering the preferred route of administration, various
requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a …

Quality by design for development, optimization and characterization of brucine ethosomal gel for skin cancer delivery

TA Ismail, TM Shehata, DI Mohamed, HS Elsewedy… - Molecules, 2021 - mdpi.com
Natural products have been extensively used for treating a wide variety of disorders. In
recent times, Brucine (BRU) as one of the natural medications extracted from seeds of nux …

Transfersome, an ultra-deformable lipid-based drug nanocarrier: an updated review with therapeutic applications

Simrah, A Hafeez, SA Usmani, MP Izhar - … -Schmiedeberg's Archives of …, 2024 - Springer
The application of nanotechnology with integration of chemical sciences is increasing
continuously in the management of diseases. The drug's physicochemical and …

Innovative topical patches for non-melanoma skin cancer: current challenges and key formulation considerations

S Kim, CM Day, Y Song, A Holmes, S Garg - Pharmaceutics, 2023 - mdpi.com
Non-melanoma skin cancer (NMSC) is the most prevalent malignancy worldwide, with
approximately 6.3 million new cases worldwide in 2019. One of the key management …

In Vitro Permeation Studies on Carvedilol Containing Dissolving Microarray Patches Quantified Using a Rapid and Simple HPLC-UV Analytical Method

QK Anjani, AHB Sabri, MB McGuckin, H Li… - AAPS …, 2022 - Springer
Analytical method validation is a vital element of drug formulation and delivery studies. Here,
high-performance liquid chromatography in conjunction with UV detection (HPLC-UV) has …

Site-specific vesicular drug delivery system for skin cancer: a novel approach for targeting

M Pandey, H Choudhury, B Gorain, SQ Tiong… - Gels, 2021 - mdpi.com
Skin cancer, one of the most prevalent cancers worldwide, has demonstrated an alarming
increase in prevalence and mortality. Hence, it is a public health issue and a high burden of …