A practical guide to amplicon and metagenomic analysis of microbiome data

YX Liu, Y Qin, T Chen, M Lu, X Qian, X Guo… - Protein & cell, 2021 - academic.oup.com
Advances in high-throughput sequencing (HTS) have fostered rapid developments in the
field of microbiome research, and massive microbiome datasets are now being generated …

[HTML][HTML] Pollen-based climate reconstruction techniques for late Quaternary studies

M Chevalier, BAS Davis, O Heiri, H Seppä… - Earth-Science …, 2020 - Elsevier
Fossil pollen records are well-established indicators of past vegetation changes. The
prevalence of pollen across environmental settings including lakes, wetlands, and marine …

Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota

K Hosomi, M Saito, J Park, H Murakami… - Nature …, 2022 - nature.com
The gut microbiome is an important determinant in various diseases. Here we perform a
cross-sectional study of Japanese adults and identify the Blautia genus, especially B …

[HTML][HTML] Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer

A Alam, E Levanduski, P Denz, HS Villavicencio… - Cancer cell, 2022 - cell.com
TH 2 cells and innate lymphoid cells 2 (ILC2) can stimulate tumor growth by secreting pro-
tumorigenic cytokines such as interleukin-4 (IL-4), IL-5, and IL-13. However, the …

Host selection shapes crop microbiome assembly and network complexity

C Xiong, YG Zhu, JT Wang, B Singh, LL Han… - New …, 2021 - Wiley Online Library
Plant microbiomes are essential to host health and productivity but the ecological processes
that govern crop microbiome assembly are not fully known. Here we examined bacterial …

Structure and function of the soil microbiome underlying N2O emissions from global wetlands

M Bahram, M Espenberg, J Pärn… - Nature …, 2022 - nature.com
Wetland soils are the greatest source of nitrous oxide (N2O), a critical greenhouse gas and
ozone depleter released by microbes. Yet, microbial players and processes underlying the …

Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease

RS Mehta, JR Mayers, Y Zhang, A Bhosle… - Nature medicine, 2023 - nature.com
For decades, variability in clinical efficacy of the widely used inflammatory bowel disease
(IBD) drug 5-aminosalicylic acid (5-ASA) has been attributed, in part, to its acetylation and …

Heat stress destabilizes symbiotic nutrient cycling in corals

N Rädecker, C Pogoreutz, HM Gegner… - Proceedings of the …, 2021 - National Acad Sciences
Recurrent mass bleaching events are pushing coral reefs worldwide to the brink of
ecological collapse. While the symptoms and consequences of this breakdown of the coral …

Gut microbiome heritability is nearly universal but environmentally contingent

L Grieneisen, M Dasari, TJ Gould, JR Björk, JC Grenier… - Science, 2021 - science.org
Relatives have more similar gut microbiomes than nonrelatives, but the degree to which this
similarity results from shared genotypes versus shared environments has been …

Robust variation in infant gut microbiome assembly across a spectrum of lifestyles

MR Olm, D Dahan, MM Carter, BD Merrill, FB Yu… - Science, 2022 - science.org
Infant microbiome assembly has been intensely studied in infants from industrialized
nations, but little is known about this process in nonindustrialized populations. We deeply …