Neuroimmune mechanisms of depression

GE Hodes, V Kana, C Menard, M Merad… - Nature neuroscience, 2015 - nature.com
Current diagnosis of depression is based solely on behavioral symptomatology. The
available US Food and Drug Administration–approved treatments for depression have come …

Immune and neuroendocrine mechanisms of stress vulnerability and resilience

C Ménard, ML Pfau, GE Hodes, SJ Russo - Neuropsychopharmacology, 2017 - nature.com
Diagnostic criteria for mood disorders including major depressive disorder (MDD) largely
ignore biological factors in favor of behavioral symptoms. Compounding this paucity of …

Neurobiology of resilience in depression: immune and vascular insights from human and animal studies

KA Dudek, L Dion‐Albert, FN Kaufmann… - European Journal of …, 2021 - Wiley Online Library
Major depressive disorder (MDD) is a chronic and recurrent psychiatric condition
characterized by depressed mood, social isolation and anhedonia. It will affect 20% of …

Neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio in depression: an updated systematic review and meta-analysis

Y Cheng, Y Wang, X Wang, Z Jiang, L Zhu… - Frontiers in …, 2022 - frontiersin.org
Background Research on neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio
(PLR), and monocyte-to-lymphocyte ratio (MLR) in depression is still emerging and has …

Going beyond the visible in type 2 diabetes mellitus: defense mechanisms and their associations with depression and health-related quality of life

G Martino, A Caputo, F Bellone… - Frontiers in …, 2020 - frontiersin.org
Introduction Clinical psychological features may impact a person's aptitude to deal with
chronic diseases, leading to emotional distress, suffering, and a worse perceived quality of …

[HTML][HTML] Hepatitis C virus-associated neurocognitive and neuropsychiatric disorders: Advances in 2015

S Monaco, S Mariotto, S Ferrari… - World Journal of …, 2015 - ncbi.nlm.nih.gov
Since its identification in 1989, hepatitis C virus (HCV) has emerged as a worldwide health
problem with roughly 185 million chronic infections, representing individuals at high risk of …

The citrus flavonoid naringenin impairs the in vitro infection of human cells by Zika virus

AHD Cataneo, D Kuczera, AC Koishi, C Zanluca… - Scientific Reports, 2019 - nature.com
The Zika virus (ZIKV) is an arthropod-borne virus that belongs to the Flaviviridae family. The
ZIKV infection is usually asymptomatic or is associated with mild clinical manifestations; …

Defensive responses to stressful life events associated with cancer diagnosis

M Miniati, M Miccoli, R Ciacchini, G Orrù… - … Journal of Clinical …, 2020 - arpi.unipi.it
Objectives: Stressful life events (SLEs) are common in patients who developed both physical
and psychological syndromes. Research shown the role of psychological defense …

Emotional suppression and oneiric expression in psychosomatic disorders: early manifestations in emerging adulthood and young patients

S Settineri, F Frisone, A Alibrandi, EM Merlo - Frontiers in psychology, 2019 - frontiersin.org
Background The function of emotions, beginning from the proto-emotions, is the adaptation
to the environment. This is based on the Homeorhesis, the equilibrium due to the adaptive …

Towards a multilevel model of major depression: genes, immuno-metabolic function, and cortico-striatal signaling

ER Paul, L Östman, M Heilig, HS Mayberg… - Translational …, 2023 - nature.com
Biological assay and imaging techniques have made visible a great deal of the machinery of
mental illness. Over fifty years of investigation of mood disorders using these technologies …