Lipid‐lowering trials are not representative of patients managed in clinical practice: a systematic review and meta‐analysis of exclusion criteria
M Aeschbacher‐Germann, N Kaiser… - Journal of the …, 2023 - Am Heart Assoc
Background Randomized clinical trials (RCTs) might not be representative of the real‐world
population because of unreasonable exclusion criteria. We sought to determine which …
population because of unreasonable exclusion criteria. We sought to determine which …
[HTML][HTML] PoLA/CFPiP/PCS/PSLD/PSD/PSH guidelines on diagnosis and therapy of lipid disorders in Poland 2021
M Banach, P Burchardt, K Chlebus… - Archives of Medical …, 2021 - ncbi.nlm.nih.gov
Moreover, over the last few years the approach to treatment of patients with a high
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …
Recommendations on deprescribing of bisphosphonates in osteoporosis guidelines: a systematic review
DB Jepsen, ES Bergen, J Pan, E van Poelgeest… - European Geriatric …, 2023 - Springer
Purpose Advancing age, declining health status, and a shift in benefit/risk balance warrant
judicious use of preventive medications in older persons, including consideration of …
judicious use of preventive medications in older persons, including consideration of …
Statin discontinuation and cardiovascular events among older people in Denmark
W Thompson, L Morin, DE Jarbøl… - JAMA network …, 2021 - jamanetwork.com
Importance Statin use is common in older persons. Given uncertainties in ongoing benefit,
changes in health status, and shifting goals of care and preferences, statin discontinuation …
changes in health status, and shifting goals of care and preferences, statin discontinuation …
Statins, mortality, and major adverse cardiovascular events among US veterans with chronic kidney disease
O Barayev, CE Hawley, H Wellman… - JAMA Network …, 2023 - jamanetwork.com
Importance There are limited data for the utility of statins for primary prevention of
atherosclerotic cardiovascular disease (ASCVD) and death in adults with chronic kidney …
atherosclerotic cardiovascular disease (ASCVD) and death in adults with chronic kidney …
New statin use, mortality, and first cardiovascular events in older US Veterans by frailty status
Background Statins are part of long‐term medical regimens for many older adults. Whether
frailty modifies the protective relationship between statins, mortality, and major adverse …
frailty modifies the protective relationship between statins, mortality, and major adverse …
Classical risk factors for primary coronary artery disease from an aging perspective through Mendelian Randomization
The significance of classical risk factors in coronary artery disease (CAD) remains unclear in
older age due to possible changes in underlying disease pathologies. Therefore, we …
older age due to possible changes in underlying disease pathologies. Therefore, we …
Discontinuation of statins in veterans admitted to nursing homes near the end of life
CT Thorpe, FE Sileanu, MK Mor, X Zhao… - Journal of the …, 2020 - Wiley Online Library
BACKGROUND/OBJECTIVES Geriatric guidelines recommend against statin use in older
adults with limited life expectancy (LLE) or advanced dementia (AD). This study examined …
adults with limited life expectancy (LLE) or advanced dementia (AD). This study examined …
Primary prevention statin therapy in older adults
MG Nanna, A Abdullah, MB Mortensen… - Current opinion in …, 2023 - journals.lww.com
Primary prevention statin therapy in older adults : Current Opinion in Cardiology Primary
prevention statin therapy in older adults : Current Opinion in Cardiology Log in or Register …
prevention statin therapy in older adults : Current Opinion in Cardiology Log in or Register …
Sex and stroke risk factors: A review of differences and impact
M Hanna, A Wabnitz, P Grewal - Journal of Stroke and Cerebrovascular …, 2024 - Elsevier
Objectives There is an increase in stroke incidence risk over the lifetime of women, given
their longer life expectancy. However, an alarming trend for sex disparities, particularly in …
their longer life expectancy. However, an alarming trend for sex disparities, particularly in …