The development of the mammalian cerebellum is orchestrated by both cell-autonomous
programs and inductive environmental influences. Here, we describe the main processes of …

The cerebellum contains the largest number of neurons and synapses of any structure in the
central nervous system. The concept that the cerebellum is solely involved in fine motor …

The internal structure of the cerebellum reflects an intriguing paradox; its cytoarchitecture is
relatively simple and repeated throughout, yet the connections between its neurons are …

Historically, the molecular and cellular mechanisms of cerebellar development were
investigated through structural descriptions and studying spontaneous mutations in animal …

Atypical teratoid/rhabdoid tumor (ATRT) is an aggressive central nervous system tumor
characterized by loss of SMARCB1/INI1 protein expression and comprises three distinct …

The inner cell mass (ICM) of the implanting mammalian blastocyst comprises two lineages:
the pluripotent epiblast (EPI) and primitive endoderm (PrE). We have identified platelet …

The elucidation of epigenetic alterations in the autism brain has potential to provide new
insights into the molecular mechanisms underlying abnormal gene expression in this …

Over the last 60 years, the spotlight of research has periodically returned to the cerebellum
as new techniques and insights have emerged. Because of its simple homogeneous …

Overreactivity and defensive behaviors in response to tactile stimuli are common symptoms
in autism spectrum disorder (ASD) patients. Similarly, somatosensory hypersensitivity has …

Heterozygous deletions encompassing the ZIC1; ZIC4 locus have been identified in a
subset of individuals with the common cerebellar birth defect Dandy-Walker malformation …