Engineering macrophages for cancer immunotherapy and drug delivery

Y Xia, L Rao, H Yao, Z Wang, P Ning… - Advanced …, 2020 - Wiley Online Library
Macrophages play an important role in cancer development and metastasis.
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …

Advances in drug delivery systems based on red blood cells and their membrane-derived nanoparticles

PHD Nguyen, MK Jayasinghe, AH Le, B Peng… - ACS nano, 2023 - ACS Publications
Red blood cells (RBCs) and RBC membrane-derived nanoparticles have been historically
developed as bioinspired drug delivery systems to combat the issues of premature …

[HTML][HTML] Extracellular vesicle-based drug delivery systems for cancer treatment

S Walker, S Busatto, A Pham, M Tian, A Suh… - Theranostics, 2019 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are naturally occurring cell-secreted nanoparticles that play
important roles in many physiological and pathological processes. EVs enable intercellular …

Cell membrane-coated mimics: a methodological approach for fabrication, characterization for therapeutic applications, and challenges for clinical translation

V Chugh, K Vijaya Krishna, A Pandit - ACS nano, 2021 - ACS Publications
Cell membrane-coated (CMC) mimics are micro/nanosystems that combine an isolated cell
membrane and a template of choice to mimic the functions of a cell. The design exploits its …

Biomaterials functionalized with MSC secreted extracellular vesicles and soluble factors for tissue regeneration

MÁ Brennan, P Layrolle… - Advanced functional …, 2020 - Wiley Online Library
The therapeutic benefits of mesenchymal stromal cell (MSC) transplantation are attributed to
their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …

Biologically modified nanoparticles as theranostic bionanomaterials

J Yang, X Zhang, C Liu, Z Wang, L Deng… - Progress in Materials …, 2021 - Elsevier
Inspired by natural biology, cell membrane-mimetic surface engineering and cell membrane
camouflaging technology have been widely investigated. Notably, the cell membrane …

Cell primitive-based biomimetic functional materials for enhanced cancer therapy

GF Luo, WH Chen, X Zeng, XZ Zhang - Chemical Society Reviews, 2021 - pubs.rsc.org
Cell primitive-based functional materials that combine the advantages of natural substances
and nanotechnology have emerged as attractive therapeutic agents for cancer therapy. Cell …

Bacterial vesicle-cancer cell hybrid membrane-coated nanoparticles for tumor specific immune activation and photothermal therapy

D Wang, C Liu, S You, K Zhang, M Li… - … applied materials & …, 2020 - ACS Publications
Cell membrane camouflaged nanoparticles (NPs) have been increasingly explored to
leverage natural cellular functions and adapt to various biomedical applications. Herein, we …

Cell membrane biomimetic nanoparticles for inflammation and cancer targeting in drug delivery

H Wang, Y Liu, R He, D Xu, J Zang… - Biomaterials …, 2020 - pubs.rsc.org
Nanoparticle capture and elimination by the immune system are great obstacles for drug
delivery. Camouflaging nanoparticles with cell membrane represents a promising strategy to …

Engineering cell membrane‐based nanotherapeutics to target inflammation

H Yan, D Shao, YH Lao, M Li, H Hu… - Advanced …, 2019 - Wiley Online Library
Inflammation is ubiquitous in the body, triggering desirable immune response to defend
against dangerous signals or instigating undesirable damage to cells and tissues to cause …