Radical lifespan disparities exist in the animal kingdom. While the ocean quahog can
survive for half a millennium, the mayfly survives for less than 48 h. The evolutionary …

Impaired synaptic plasticity is implicated in the functional decline of the nervous system
associated with ageing. Understanding the structure of ageing synapses is essential to …

Experimental, clinical, and epidemiological findings support the concept of developmental
origins of health and disease (DOHAD), suggesting that early-life hormonal influences …

Abstract Resveratrol (3, 4′, 5-trihydroxystilbene) is a plant-derived polyphenolic trans-
stilbenoid, which exerts multifaceted antiaging effects. Here, we propose a novel delivery …

Among several theories to explain the complicated process of human ageing, the
mitochondrial oxidative stress hypothesis has received recent attention. Considering that …

Bivalve mollusks have several unique traits, including some species with exceptionally long
lives, others with very short lives, and the ability to determine the age of any individual from …

The field of sclerochronology has long been known to paleobiologists. Yet, despite the
central role of growth rate, age, and body size in questions related to macroevolution and …

Proteome damage plays a major role in aging and age-related neurodegenerative diseases.
Under healthy conditions, molecular quality control mechanisms prevent toxic protein …

Bay scallops are commercially important bivalve species for fisheries and aquaculture in
China, the USA, Peru and Chile, but their small size, short lifespan (< 14 months) and …

The maintenance of genomic integrity through the DNA repair processes is essential for
proper cellular metabolism, growth, and development. DNA damage plays a key role in …