Sjögren's syndrome is a chronic and insidious auto-immune disease characterized by
lymphocyte infiltration of exocrine glands. The patients typically present with ocular surface …

Sjogren's syndrome (SS) is a chronic autoimmune disease characterized by the infiltration of
exocrine glands including salivary and lachrymal glands responsible for the classical dry …

There is currently no approved treatment for primary Sjögren's syndrome, a disease that
primarily affects adult women. The difficulty in developing effective therapies is-in part …

Summary Background Primary Sjögren's syndrome is a systemic autoimmune disease
characterised by secretory gland dysfunction, for which no effective therapy is available …

The pathogenesis of primary Sjögren's syndrome (pSS) remains poorly understood.
However, important efforts have been made during the last few months. In this review …

Plasmacytoid dendritic cells (pDCs) are a unique subpopulation of immune cells, distinct
from classical dendritic cells. pDCs are generated in the bone marrow and following …

Objectives To systematically review the literature for assay methods that aim to evaluate type
I interferon (IFN-I) pathway activation and to harmonise-related terminology. Methods Three …

There are some challenges and unmet needs in the early diagnosis and management of
Sjögren's syndrome (SjS) such as prominent glandular dysfunction at diagnosis and long …

Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease characterized
primarily by immune-mediated destruction of exocrine tissues, such as those of the salivary …

Extraglandular manifestations (EGMs) in primary Sjogren's syndrome (pSS) represent the
clinical expression of the systemic involvement in this disease. EGMs are characterized by a …